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Table 3 Maximum acute and late GI and GU toxicity

From: Long-term results of a phase II study of hypofractionated proton therapy for prostate cancer: moderate versus extreme hypofractionation

Maximum grade

MHF (n = 52)

EHF (n = 30)

P

Total (n = 82)

Acute toxicity

 GI

  0

46 (89%)

24 (80%)

.341b)

70 (85%)

  1

6 (11%)

6 (20%)

 

12 (15%)

 GU

  0

8 (15%)

13 (43%)

.009b)

21 (26%)

  1

42 (81%)

15 (50%)

 

57 (70%)

  2

2 (4%)

2 (7%)

 

4 (5%)

Late toxicity

 GI

  0

15 (29%)

10 (33%)

.891b)

25 (31%)

  1

27 (52%)

16 (53%)

 

43 (52%)

  2

8 (15%)

4 (13%)

 

12 (15%)

 3

2 (4%)

0 (0%)

 

2 (2%)

 GUa)

  0

32 (62%)

19 (63%)

.835a)

51 (62%)

  1

14 (27%)

9 (30%)

 

23 (28%)

  2

6 (12%)

2 (7%)

 

8 (10%)

  1. MHF moderate hypofractionation, EHF extreme hypofractionation, GI gastrointestinal, GU genitourinary
  2. a)Chi-square test
  3. b)Fisher’s exact test