Table 2 Distribution of the patient treatment and clinical characteristics in two treatment groups
Characteristics | WBRT (%) | WBRT plus boost (%) | P value |
|---|---|---|---|
Sex (male) | 41 (81.7) | 23 (69.7) | 0.134 |
Age (median) | 59 | 61 | 0.572 |
KPS ≥ 70 | 43 (87.8) | 33 (100) | 0.057 |
Smoking history(yes) | 37 (75.5) | 27 (81.8) | 0.499 |
Weight loss>5% | 18 (36.7) | 8 (24.2) | 0.333 |
Number of BM | |||
1 | 5 (10.2) | 16 (48.5) | 0.0001* |
2–3 | 13 (26.5) | 11 (33.3) | |
> 3 | 31 (63.3) | 6 (18.2) | |
Interval from diagnosis of SCLC to BMs (< 10 month) | 21 (42.9) | 18 (56.2) | 0.238 |
Maximum diameter of the largest tumor (≤2.0 cm) | 23 (46.9) | 17 (51.5) | 0.213 |
Treatment regimen before BM (Sequential CRT) | 36 (73.5) | 18 (54.5) | 0.076 |
Symptomatic BM | 18 (36.7) | 9 (27.3) | 0.371 |
Progressive extracranial diseases | 11 (22.4) | 4 (12.1) | 0.236 |