Table 2 Summary of average ± s.d. doses to PTVs and OAR for the 20 patients in Set_2
Structure | Parameter | a - Clinical | b - Clinical + TO | c - RP_1 | d - RP_1 + TO | e - RP_TO | f - RP_ TO+ |
|---|---|---|---|---|---|---|---|
PTV 1 | D99% > 90% p < 0.05 | 93.7 ± 0.9 c | 94.1 ± 2.0 | 94.2 ± 1.2 a,e | 93.8 ± 2.5 | 93.6 ± 1.5 c | 93.7 ± 2.3 |
D95% > 95% p < 0.05 | 96.1 ± 0.6 b,c,d | 96.8 ± 0.8 a,c,e,f | 96.3 ± 0.7 a,b,e | 96.6 ± 1.0 a,e | 96.0 ± 0.9 b,c,d,f | 96.4 ± 0.9 b,e | |
D5% < 105% p < 0.05 | 102.9 ± 0.5 b,d | 102.4 ± 0.5 a,c,e,f | 102.7 ± 0.4 b,d,e | 102.4 ± 0.7 a,c,e,f | 103.1 ± 0.6 b,c,d, | 102.8 ± 0.8 b,d, | |
D2% < 107% p < 0.05 | 103.5 ± 0.7 b,d,e | 103.0 ± 0.8 a,c,e,f | 103.4 ± 0.6 b,e | 103.5 ± 0.9 a,e,f | 103.8 ± 0.8 a,b,c,d | 103.7 ± 1.2 b,d | |
HI p < 0.05 | 1.07 ± 0.01 b,c,d | 1.06 ± 0.01 a,c,e,f | 1.07 ± 0.01 a,b,d,e | 1.06 ± 0.02 a,e,f | 1.07 ± 0.01 b,c,d,f | 1.07 ± 0.02 b,d,e | |
PTV LR | D99% > 74.8% p < 0.05 | 77.4 ± 0.6 c,f | 77.1 ± 1.0 c,f | 78.4 ± 0.7 a,b,d,e,f | 77.0 ± 1.4 c,f | 77.5 ± 1.0 c,f | 76.0 ± 1.2 a,b,c,d,e |
D95% > 78.9% p < 0.05 | 79.7 ± 0.4 b,c,d,f | 81.1 ± 0.9 a,c,e | 80.2 ± 0.5 a,b,d,e,f | 81.2 ± 0.6 a,c,e | 79.9 ± 0.6 b,c,d,f | 80.8 ± 0.9 a,c,e | |
HI p < 0.05 | 1.13 ± 0.02 b,c,d,f | 1.16 ± 0.02 a,c,e,f | 1.12 ± 0.01 a,b,d,e,f | 1.16 ± 0.02 a,c,e,f | 1.13 ± 0.01 b,c,d,f | 1.17 ± 0.02 a,b,c,d,e | |
PRV Brainstem | DMax < 48Gy p < 0.05 | 26.9 ± 15.7 b,c,d,e,f | 24.3 ± 14.5 a,f | 25.9 ± 14.8 a,d,e,f | 23.2 ± 13.3 a, c, | 23.9 ± 13.5 a,c,f | 20.9 ± 11.6 a,b,c,e |
PRV Spinal Cord | D1% < 44Gy p < 0.05 | 37.6 ± 2.7 b,c,d,e,f | 32.7 ± 2.9 a,c,d,f | 36.4 ± 2.2 a,b,d,e,f | 30.5 ± 3.1 a,b,c,f | 31.5 ± 3.0 a,c,f | 27.5 ± 4.7 a,b,c,d,e |
DMax < 48Gy p < 0.05 | 40.4 ± 2.9 b,d,e,f | 35.1 ± 2.9 a,c,f | 39.3 ± 2.2 b,d,e,f | 33.6 ± 3.4 a,c,f | 34.3 ± 3.5 a,c,f | 30.8 ± 4.9 a,b,c,d,e | |
Left Parotid | DMean < 24Gy p < 0.05 | 22.9 ± 5.5 b,d,e,f | 16.7 ± 4.8 a,c,f | 22.3 ± 5.5 b,d,e,f | 16.7 ± 4.5 a,c,f | 16.8 ± 4.9 a,c,f | 15.0 ± 4.6 a,b,c,d,e |
Right Parotid | DMean < 24Gy p < 0.05 | 24.8 ± 5.8 b,d,e,f | 19.1 ± 4.4 a,c,f | 24.2 ± 5.4 b,d,e,f | 18.4 ± 4.7 a,c,f | 19.0 ± 5.9 a,c,f | 17.1 ± 5.0 a,b,c,d,e |
CI | V100%/VPTVs p < 0.05 | 0.27 ± 0.08 b,d, | 0.29 ± 0.09 a,c,e | 0.27 ± 0.08 b,d,f | 0.29 ± 0.09 a,c | 0.28 ± 0.09 b, | 0.29 ± 0.09 c, |
V80%/VPTVs p < 0.05 | 1.26 ± 0.14 b,d,f | 1.47 ± 0.15 a,c,d,e,f | 1.23 ± 0.06 b,d,f | 1.40 ± 0.08 a,b,c,e | 1.24 ± 0.06 b,d,f | 1.41 ± 0.07 a,b,c,e | |
V50%/VPTVs p < 0.05 | 2.55 ± 0.33 b,d,f | 2.94 ± 0.41 a,c,d,e,f | 2.49 ± 0.19 b,d,e,f | 2.79 ± 0.25 a,b,c,e | 2.52 ± 0.21 b,c,d,f | 2.84 ± 0.29 a,b,c,e | |
V10%/VPTVs p < 0.05 | 9.31 ± 1.89 b,d,f | 9.55 ± 1.90 a,c,d,e,f | 9.28 ± 1.84 b,d,f | 9.41 ± 1.81 a,b,c,e | 9.28 ± 1.81 b,d,f | 9.39 ± 1.78 a,b,c,e | |
Right Parotid | DMean < 24Gy p < 0.05 | 24.8 ± 5.8 b,d,e,f | 19.1 ± 4.4 a,c,f | 24.2 ± 5.4 b,d,e,f | 18.4 ± 4.7 a,c,f | 19.0 ± 5.9 a,c,f | 17.1 ± 5.0 a,b,c,d,e |
Total Fails | Parameters | 22 | 2 | 20 | 4 | 11 | 3 |
Plans | 13 | 2 | 13 | 3 | 7 | 2 |