Skip to main content

Table 3 Radiation doses according to the change in cIBS

From: Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer

Structure

≥15% increase in cIBS (n = 29)

< 15% increase in cIBS (n = 35)

 

Md (IQR)

Md (IQR)

p

Heart

 Dmean (Gy)

3.4 (1.1–4.2)

1.6 (0.8–2.7)

0.011

 Dmax (Gy)

47.2 (15.0–48.8)

44.5 (6.4–47.1)

0.068

 V45 (%)

0.5 (0–1.7)

0 (0–0.4)

0.025

 V20 (%)

4.4 (0–6.2)

1.1 (0–2.4)

0.005

LAD

 Dmean (Gy)

22.9 (2.3–27.3)

7.3 (0.4–18.0)

0.042

 Dmax (Gy)

45.9 (5.3–46.8)

36.3 (0.6–45.3)

0.040

 V45 (%)

0.4 (0–13.9)

0 (0–0.3)

0.008

 V20 (%)

42.7 (0–68.7)

8.9 (0–38.4)

0.041

Left ventricle

 Dmean (Gy)

4.9 (1.2–7.0)

2.3 (0.2–3.8)

0.023

 Dmax (Gy)

45.8 (9.0–47.8)

41.7 (0.7–45.9)

0.080

 V45 (%)

0.1 (0–2.9)

0 (0–0.2)

0.006

 V20 (%)

6.7 (0–10.4)

1.3 (0–4.7)

0.021

 V10 (%)

9.0 (0–15.0)

3.0 (0–6.5)

0.006

Right ventricle (n = 49)

 Dmean (Gy)

2.4 (1.1–3.1)

1.5 (0.9–2.3)

0.074

 Dmax (Gy)

29.6 (3.6–44.0)

8.1 (3.0–39.3)

0.189

 V45 (%)

0 (0–0)

0 (0–0)

0.150

 V20 (%)

0.1 (0–2.7)

0 (0–0.4)

0.053

 V10 (%)

0.9 (0–6.5)

0 (0–1.4)

0.019

Lung

 Dmean (Gy)

8.2 (7.6–9.6)

6.8 (5.5–8.2)

0.001

 Dmax (Gy)

50.1 (47.9–56.7)

47.5 (46.4–49.7)

0.009

  1. Md median, IQR interquartile range, Dmean mean radiation dose to the structure, Dmax maximum radiation dose within the structure, V45 percentage of the structure volume receiving 45 Gy of radiation, V20 percentage of the structure volume receiving 20 Gy of radiation, V10 percentage of the structure volume receiving 10 Gy of radiation, LAD left anterior descending coronary artery