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Table 1 OAR dose constraints applied for three fraction SABR in this study

From: Stereotactic ablative radiotherapy (SABR) as primary, adjuvant, consolidation and re-treatment option in pancreatic cancer: scope for dose escalation and lessons for toxicity

 

D0.035 cc

D0.1 cc

D10.0 cc

D5.0 cc

V12 Gy

V15 Gy

V21 Gy

Duodenum

≤ 22.2 Gy

–

≤ 11.4 Gy

≤ 16.5 Gy

–

–

–

Stomach

≤ 22.2 Gy

–

≤ 16.5 Gy

–

–

–

–

Small Bowel

≤ 25.2 Gy

–

–

≤ 17.7 Gy

–

–

–

Liver

–

–

–

–

–

≤ 50%

≤ 30%

Kidneys (separate)

–

–

–

–

≤ 25%

–

–

Kidneys (together)

–

–

–

–

–

≤ 35%

–

Spinal cord

≤ 21.0 Gy

≤ 18.0 Gy

–

–

–

–

–

  1. Note: For all pancreatic patients treated with ≤ 30 Gy in three fractions, we have since revised our duodenal D0.035 cc constraint to the higher limit of 24 Gy, but additionally now use D1.0 cc < 31.4 Gy
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Radiation Oncology

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