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Table 3 Results of Spearman’s correlation tests between parotid shrinkage and imaging/ anthropometric parameters at baseline

From: Radiation-induced parotid changes in oropharyngeal cancer patients: the role of early functional imaging and patient−/treatment-related factors

Variable at baseline

∆Vol10fr(%)

∆Volpost(%)

Spearman’s Rho

p-value

Spearman’s Rho

p-value

ADC

− 0.185

0.100

−0.010

0.932

Dt

−0.099

0.385

−0.061

0.609

f

−0.056

0.620

−0.002

0.986

D*

−0.019

0.865

−0.188

0.109

D* × f

−0.007

0.950

−0.167

0.154

Ktrans

0.210

0.069

0.434

< 0.001

Kep

0.239

0.038

0.349

0.003

ve

0.025

0.832

0.174

0.143

IAUGC

0.139

0.231

0.375

0.001

Parotid volume

−0.242

0.031

−0.056

0.636

Age

−0.108

0.341

0.045

0.702

Weight

−0.396

< 0.001

−0.135

0.253

BMI

−0.368

0.001

−0.127

0.281

Dmean(Gy)

0.226

0.044

−0.007

0.951

V30(%)

0.266

0.017

0.086

0.468

  1. Statistically significant p-values are bold. Abbreviations: ∆Vol10fr Parotid shrinkage(%) at the 10th fraction, ∆Volpost Parotid shrinkage(%) 8 weeks after RT, ADC Apparent diffusion coefficient, Dt Tissue diffusion coefficient, D* Perfusion-related diffusion coefficient, f(%) Perfusion fraction, D* × f Product of D* by f, ∆ADC ADC variation (%) relative to the pretreatment value (analogously for the other imaging variables), Ktrans Transfer constant between plasma and EES (extravascular extracellular space), Kep Transfer constant between EES and plasma, ve Fractional volume of EES, IAUGC Initial area under gadolinium concentration curve, BMI Body mass index, Dmean Planned mean dose to the parotid gland, V30(%) Percentage of parotid volume receiving a dose ≥30 Gy
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Radiation Oncology

ISSN: 1748-717X

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