Early toxicity and patient reported quality-of-life in patients receiving proton therapy for localized prostate cancer: a single institutional review of prospectively recorded outcomes

Table 3 Patient-reported QOL results

	Baseline			Follow Up		Mean Change at 1 Year after Treatment			Mean Annualized Change after 1 Year
QOL Measure	No. of Patients	Median (Range)	Mean ± SD	No. of Patients	No. of Visits	Value	(95% CI)	P-value^a	Value	(95% CI)	P-value^a
EPIC Bowel	164	96 (61–100)	93.4 ± 8.5	100	183	−5.4	(−8.2, −2.5)	< 0.001	−1.2	(−5.2, 2.9)	0.57
IPSS	178	6 (0–28)	8.7 ± 6.6	130	241	0.5	(−0.7, 1.8)	0.40	−0.5	(−1.9, 1.0)	0.54
IPSS Bother	173	2 (1–7)	2.5 ± 1.4	125	221	0.3	(−0.1, 0.7)	0.12	−0.2	(−0.6, 0.2)	0.32
Nocturia	181	1 (0–8)	1.8 ± 1.5	123	217	0.3	(−0.0, 0.5)	0.077	−0.2	(−0.5, 0.2)	0.33
SHIM^a	107	18 (0–25)	16.5 ± 7.1	66	123	−3.7	(−5.9, −1.4)	0.001	1.8	(−1.3, 5.0)	0.25

ISSN: 1748-717X