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Table 3 Univariate and multivariate analysis of the associations between factors affecting OS and PFS in patients

From: Induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus volumetric modulated arc therapy alone in the treatment of stage II-IVB nasopharyngeal carcinoma patients: a retrospective controlled study

Outcome Univariate Multivariate
P-value Hazard ratio (95% CI) P-value
Overall survival
 Sex female vs. male 0.24 0.57 (0.22–1.47) 0.24
 Age ≤ 54 years vs. > 54 years 0.003a 0.43 (0.22–0.82) 0.01a
 T category T1–2 vs.T3–4 0.001a 0.52 (0.27–0.99) 0.046a
 N category N0-1vs. N2–3 0.001a 0.34 (0.13–0.85) 0.02a
 Treatment arm ICRT vs. IC/CCRT 0.84 1.35 (0.70–2.61) 0.37
Progression-free survival
 Sex female vs. male 0.49 0.74 (0.39–1.39) 0.34
 Age ≤ 54 years vs. > 54 years < 0.001a 0.36 (0.21–0.60) < 0.001a
 T category T1–2 vs.T3–4 0.01a 0.67 (0.40–1.14) 0.14
 N category N0-1vs. N2–3 0.003a 0.49 (0.26–0.93) 0.03a
 Treatment arm ICRT vs. IC/CCRT 0.19 1.62 (0.94–2.79) 0.08
  1. ICRT induction chemotherapy plus radiotherapy, ICCCRT concurrent chemotherapy plus radiotherapy, CI confidence interval
  2. astatistical significant