Radiation Oncology

Table 3 Univariate and multivariate analysis of the associations between factors affecting OS and PFS in patients

From: Induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus volumetric modulated arc therapy alone in the treatment of stage II-IVB nasopharyngeal carcinoma patients: a retrospective controlled study

Outcome	Univariate	Multivariate
Outcome	P-value	Hazard ratio (95% CI)	P-value
Overall survival
Sex female vs. male	0.24	0.57 (0.22–1.47)	0.24
Age ≤ 54 years vs. > 54 years	0.003^a	0.43 (0.22–0.82)	0.01^a
T category T1–2 vs.T3–4	0.001^a	0.52 (0.27–0.99)	0.046^a
N category N0-1vs. N2–3	0.001^a	0.34 (0.13–0.85)	0.02^a
Treatment arm ICRT vs. IC/CCRT	0.84	1.35 (0.70–2.61)	0.37
Progression-free survival
Sex female vs. male	0.49	0.74 (0.39–1.39)	0.34
Age ≤ 54 years vs. > 54 years	< 0.001^a	0.36 (0.21–0.60)	< 0.001^a
T category T1–2 vs.T3–4	0.01^a	0.67 (0.40–1.14)	0.14
N category N0-1vs. N2–3	0.003^a	0.49 (0.26–0.93)	0.03^a
Treatment arm ICRT vs. IC/CCRT	0.19	1.62 (0.94–2.79)	0.08

ICRT induction chemotherapy plus radiotherapy, ICCCRT concurrent chemotherapy plus radiotherapy, CI confidence interval
^astatistical significant

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