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Table 2 Myelotoxicity

From: Comparison of definite chemoradiation therapy with carboplatin/paclitaxel or cisplatin/5-fluoruracil in patients with squamous cell carcinoma of the esophagus

Myelotoxicity Intention to treat Per protocol
Carb/TAX
n = 22
CDDP/5FU
n = 25
p-value Carb/TAX
n = 18
CDDP/5FU
n = 23
p-value
≥ III 12 (55%) 13 (52%) 1.000 8 (44%) 12 (52%) 0.756
Leukopenia 0.634    0.719
 0° 1 (5%) 3 (12%)   1 (6%) 2 (9%)  
 I° 2 (9%) 3 (12%)   1 (6%) 3 (13%)  
 II° 9 (41%) 7 (28%)   8 (44%) 7 (30%)  
 III° 10 (45%) 10 (40%)   8 (44%) 9 (39%)  
 IV° 0 (0%) 2 (8%)   0 (0%) 2 (9%)  
Thrombocytopenia 0.960    0.364
 0° 13 (59%) 16 (64%)   12 (67%) 15 (65%)  
 I° 5 (23%) 4 (16%)   5 (28%) 3 (13%)  
 II° 3 (14%) 3 (12%)   1 (6%) 3 (13%)  
 III° 1 (5%) 2 (8%)   0 (0%) 2 (9%)  
Anemia 0.256    0.854
 0° 0 (0%) 1 (4%)   0 (0%) 1 (4%)  
 I° 11 (50%) 13 (52%)   10 (56%) 12 (52%)  
 II° 8 (36%) 11 (44%)   7 (39%) 10 (43%)  
 III° 3 (14%) 0 (0%)   1 (6%) 0 (0%)