Table 2 Myelotoxicity
Myelotoxicity | Intention to treat | Per protocol | ||||
|---|---|---|---|---|---|---|
Carb/TAX n = 22 | CDDP/5FU n = 25 | p-value | Carb/TAX n = 18 | CDDP/5FU n = 23 | p-value | |
≥ III | 12 (55%) | 13 (52%) | 1.000 | 8 (44%) | 12 (52%) | 0.756 |
Leukopenia | 0.634 | 0.719 | ||||
0° | 1 (5%) | 3 (12%) | 1 (6%) | 2 (9%) | ||
I° | 2 (9%) | 3 (12%) | 1 (6%) | 3 (13%) | ||
II° | 9 (41%) | 7 (28%) | 8 (44%) | 7 (30%) | ||
III° | 10 (45%) | 10 (40%) | 8 (44%) | 9 (39%) | ||
IV° | 0 (0%) | 2 (8%) | 0 (0%) | 2 (9%) | ||
Thrombocytopenia | 0.960 | 0.364 | ||||
0° | 13 (59%) | 16 (64%) | 12 (67%) | 15 (65%) | ||
I° | 5 (23%) | 4 (16%) | 5 (28%) | 3 (13%) | ||
II° | 3 (14%) | 3 (12%) | 1 (6%) | 3 (13%) | ||
III° | 1 (5%) | 2 (8%) | 0 (0%) | 2 (9%) | ||
Anemia | 0.256 | 0.854 | ||||
0° | 0 (0%) | 1 (4%) | 0 (0%) | 1 (4%) | ||
I° | 11 (50%) | 13 (52%) | 10 (56%) | 12 (52%) | ||
II° | 8 (36%) | 11 (44%) | 7 (39%) | 10 (43%) | ||
III° | 3 (14%) | 0 (0%) | 1 (6%) | 0 (0%) | ||