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Table 1 Nucleus – cytoplasm dose ratio together with the relative effectiveness (found in Fig. 11), the average LET and the relative LET-based RBE compared to the external irradiation for Am241 isotopes in virtual spheroid according to various spatial distributions of isotopes

From: Fluorescent nuclear track detectors for alpha radiation microdosimetry

Isotope distribution:

In Nucleus

In Cytoplasm

On Nuclear membrane

On Cell Membrane

Nucleus – Cytoplasm dose ratio

140%

94%

125%

95%

Relative effectiveness a

151%

104%

133%

105%

Average LET (keV/μm)

102 ± 36

128 ± 38

104 ± 49

129 ± 37

LET-based RBE a

0.91

0.93

0.85

0.93

  1. a relative to the external irradiation
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Radiation Oncology

ISSN: 1748-717X

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