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Table 2 Comparison of dosimetric parameters between autoVMAT and manVMAT plans. Population mean values for the 20 study patients and corresponding standard deviations are reported

From: Automated VMAT planning for postoperative adjuvant treatment of advanced gastric cancer

Structure Parameter autoVMAT manVMAT – autoVMAT
Mean ± SD Mean diff. ± SD p-value
PTV V95% (%) 97.4 ± 1.0 - 0.8 ± 1.7 0.085
D98% (Gy) 42.5 ± 0.5 - 0.2 ± 0.7 0.14
D2% (Gy) 46.3 ± 0.1 0.5 ± 0.2 <  0.001
HI 0.09 ± 0.01 0.02 ± 0.02 0.003
CI 0.91 ± 0.02 - 0.04 ± 0.03 <  0.001
Left Kidney Dmean (Gy) 12.7 ± 4.3 1.8 ± 1.6 0.001
D30% (Gy) 14.9 ± 8.1 2.1 ± 3.3 0.013
D50% (Gy) 8.9 ± 3.5 2.4 ± 2.2 0.002
D60% (Gy) 7.3 ± 1.9 2.4 ± 1.4 <  0.001
V12Gy (%) 32.2 ± 14.0 11.7 ± 7.7 <  0.001
V20Gy (%) 19.2 ± 13.2 1.0 ± 3.9 0.117
NTCP (%) 45.1 ± 35.8 11.3 ± 10.9 0.001
Right Kidney Dmean (Gy) 7.5 ± 1.7 3.0 ± 1.2 <  0.001
D30% (Gy) 7.8 ± 1.7 4.1 ± 1.6 <  0.001
D50% (Gy) 6.1 ± 1.3 3.1 ± 1.3 <  0.001
D60% (Gy) 5.5 ± 1.2 2.7 ± 1.1 <  0.001
V12Gy (%) 12.4 ± 4.8 18.9 ± 8.4 <  0.001
V20Gy (%) 3.8 ± 2.8 3.0 ± 2.8 0.001
NTCP (%) 4.2 ± 3.8 12.8 ± 7.2 <  0.001
Liver - PTV Dmean (Gy) 18.6 ± 3.3 1.8 ± 2.8 0.02
D30% (Gy) 21.9 ± 4.1 2.8 ± 3.2 0.003
D50% (Gy) 17.1 ± 3.6 1.7 ± 3.3 0.048
D60% (Gy) 15.1 ± 3.4 1.2 ± 3.3 0.14
V24Gy (%) 25.4 ± 11.6 7.1 ± 8.8 0.004
V30Gy (%) 12.9 ± 6.0 4.7 ± 4.6 0.001
NTCP (%) 31.1 ± 23.2 7.0 ± 7.0 0.001
Heart Dmean (Gy) 12.7 ± 4.7 0.7 ± 1.8 0.117
Dmax (Gy) 46.8 ± 0.6 0.8 ± 1.2 0.009
Spinal cord Dmean (Gy) 13.9 ± 2.6 2.9 ± 1.5 <  0.001
Dmax (Gy) 31.6 ± 2.6 6.7 ± 3.2 <  0.001
Left Lung Dmean (Gy) 7.3 ± 3.2 0.6 ± 0.3 <  0.001
V5Gy (%) 32.7 ± 15.6 1.4 ± 1.0 <  0.001
V20Gy (%) 14.0 ± 7.2 2.2 ± 1.8 <  0.001
Right Lung Dmean (Gy) 5.4 ± 3.3 0.3 ± 0.5 0.013
V5Gy (%) 31.2 ± 16.8 1.1 ± 2.1 0.01
V20Gy (%) 7.0 ± 7.6 0.8 ± 1.8 0.078
Patient Dmean (Gy) 9.4 ± 1.9 0.5 ± 0.3 <  0.001
V5Gy (%) 40.2 ± 8.9 1.6 ± 0.8 <  0.001
V11.25Gy (%) 30.0 ± 6.6 1.8 ± 1.7 0.001
V22.5Gy (%) 16.2 ± 3.3 1.5 ± 1.1 <  0.001
  1. Abbreviations: HI homogeneity index, CI conformity index, NTCP normal tissue complication probability