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Fig. 1 | Radiation Oncology

Fig. 1

From: Dosimetric feasibility of 4DCT-ventilation imaging guided proton therapy for locally advanced non-small-cell lung cancer

Fig. 1

Schematic diagram for creating anatomical treatment plan and 4DCT ventilation image-based functional plan and quantifying impact of functional planning. Step I-4DCT image acquisition; Step-II: to obtain the deformation vector fields (DVFs) using deformable image registration on 4DCT images; Step-III: Jacobian analysis of the DVFs to obtain regional ventilation map; Step-IV: segmentation of three functional lung regions with equal volumes: low-functional (yellow), medium-functional (blue), and high-functional (orange) lung with ITV showing red. The obtained result is used to create functional proton plans to further avoid high-functional lung regions

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