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Table 2 Relative deviations in DV and VD in PTVs and main OARs between the 3D reconstructed dose and planned dose

From: Retrospective dosimetry study of intensity-modulated radiation therapy for nasopharyngeal carcinoma: measurement-guided dose reconstruction and analysis

 

V100%

V95%

V60 Gy

V30 Gy

D98%

D95%

D1cc

Dmean

PTVnx

 Δ(%)

2.93 ± 5.03

−0.84 ± 1.59

 

−1 ± 1.39

−0.67 ± 1.39

 

0.02 ± 1.52

 Range (%)

[−15.66,5.25]

[−6.25,1.23]

 

[−3.82,1.34]

[−3.42,1.83]

[−2.93,2.97]

p

0.003

0.142

0.007

0.013

0.933

PTV1

 Δ(%)

−0.37 ± .062

− 0.08 ± 0.16

 

−1 ± 1.43

− 0.95 ± 1.32

 

 Range (%)

[−3.00,0.41]

[−0.63,0.04]

 

[−4.58,0.78]

[−3.69,1.09]

 

p

0.003

0.016

0.00

0.00

PTV2

 Δ(%)

−0.37 ± 0.48

− 0.14 ± 0.20

 

− 0.95 ± 1.43

− 0.19 ± 1.21

 

 Range (%)

[−1.26,1.10]

[−0.78,0.32]

 

[−4.15,2.47]

[−2.96,3.19]

 

p

0.000

0.001

0.001

0.39

Spinal Cord

 Δ(%)

 

0.62 ± 1.91

 

 Range (%)

[−3.22,6.66]

p

0.088

Brain Stem

 Δ(%)

 

−0.62 ± 1.2

 

−0.73 ± 1.84

 

 Range (%)

[−3.49,0.34]

[−4.80,3.84]

p

0.008

0.039

Left Parotid Gland

 Δ(%)

 

−1.40 ± 2.59

 

−1.33 ± 1.59

 Range (%)

[−12.11,1.43]

[−4.69,2.00]

p

0.006

0.00

Right Parotid Gland

 Δ(%)

 

−1.27 ± 1.49

 

−1.45 ± 1.54

 Range (%)

[−4.78,2.16]

[−4.30,1.85]

p

0.000

0.000

Left Temporal Lobe

 Δ(%)

 

−1.40 ± 2.42

 

 Range (%)

[−9.42,3.90]

p

0.004

Right Temporal Lobe

 Δ(%)

 

−1.66 ± 3.49

 

 Range (%)

[−16.02,3.64]

p

0.014

Larynx

 Δ(%)

 

1.17 ± 1.58

 Range (%)

[−2.43,5.08]

p

0.000

  1. Note. Δ(%) represents the relative deviation between the 3D reconstructed and planned doses (average ± standard deviation). p indicates significance on the two-tailed Student t-test
  2. Abbreviations:D V - volumetric dose and V D - dose volumes; PTV - planning target volume; OAR – organ at risk