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Table 1 Patients’ characteristics

From: Outcome after PSMA PET/CT based radiotherapy in patients with biochemical persistence or recurrence after radical prostatectomy

 

All patients

PSA relapse

PSA persistence

N

129

62

67

Median age

72 (47–83)

74 (50–83)

70 (47–83)

Tumor stage

 pT2

43 (33%)

35 (57%)

8 (12%)

 pT3a

36 (28%)

17 (27%)

19 (28%)

 pT3b

48 (37%)

8 (13%)

40 (60%)

 pT4

2 (2%)

2 (3%)

–

Nodal stage

 pN0

79 (61%)

46 (74%)

33 (49%)

 pN1

37 (29%)

8 (13%)

29 (43%)

 pNx/cN0

13 (10%)

8 (13%)

5 (8%)

Positive surgical margins

60 (47%)

16 (26%)

44 (66%)

Gleason score

 6–7

70 (54%)

44 (71%)

26 (39%)

 8–9

59 (46%)

18 (29%)

41 (61%)

Median PSA at RPE

10.85 (2.37–190)

8.55 (2.37–48)

18.05 (3.99–190)

Postoperative PSA

0.12 (< 0.03–40.13)

< 0.03

0.47 (0.08–40.13)

Months since RPE

33 (2–192)

61 (9–192)

8 (2–94)

Median PSA at PSMA PET/CT

0.62 (0.13–40.13)

0.44 (0.15–6.24)

0.90 (0.13–40.13)

Median PSA at PSMA PET/CT in PET positive pts

1.09 (0.14–40.13)

0.78 (0.27–6.24)

1.6 (0.14–40.13)

Median PSA at PSMA PET/CT in PET negative pts

0.3 (0.13–3.24)

0.3 (0.13–3.24)

0.34 (0.13–1.33)

PSMA PET/CT result

 Negative

51 (39%)

31 (50%)

20 (30%)

 Fossa recurrence only

24 (19%)

16 (26%)

8 (12%)

 Lymph node positive only

42 (33%)

12 (19%)

30 (45%)

 Fossa and lymph node recurrence

12 (9%)

3 (5%)

9 (13%)

  1. Pts patients, PSA prostate specific antigen, RPE radical prostatectomy, PSMA PET/CT prostate-specific membrane antigen positron emission tomography/computed tomography