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Table 3 Multivariate Cox regression analysis for loco-regional recurrence-free survival (LRFS) and overall survival (OS) for DCIS

From: Role of postoperative radiotherapy in reducing ipsilateral recurrence in DCIS: an observational study of 1048 cases

 

LRFS

OS

Variable

HR

95% CI

p

HR

95% CI

p

Age at diagnosis

  

0.089

  

< 0.001

  < 50 years

1

  

1

  

 50–69 y

1.014

0.625–1.645

 

4.809

0.639–36.165

 

  ≥ 70 y

0.423

0.180–0.994

 

34.505

4.594–259.164

 

Radiotherapy

  

0.008

  

0.069

 yes

0.579

0.384–0.872

 

0.526

0.263–1.052

 

 no

1

  

1

  

Multifocality

  

0.818

  

0.790

 yes

1

  

1

  

 no

1.125

0.412–3.077

 

0.822

0.194–3.482

 

Resection margins

  

0.424

  

0.948

 R0

1

  

1

  

 R1–2

1.449

0.583–3.602

 

1.049

0.246–4.474

 

Endocrine Therapy

  

0.097

  

0.274

 yes

1

  

1

  

 no

1.710

0.906–3.226

 

0.621

0.265–1.458