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Table 2 Dose to the OARs for different treatment techniques

From: Cerebral cortex dose sparing for glioblastoma patients: IMRT versus robust treatment planning

OAR IMRT IMRT with CS Robust Robust with CS
TVa (D50) 60.0 60.0 60.0 60.0
± 0.0 ± 0.0 ± 0.0 ± 0.0
Brainstem (D1) 51.8 51.7 51.3 50.8
± 17.5 ± 17.5 ± 17.5 ± 17.3
Cerebellum (D50) 15.5 15.2 14.3 14.3
± 17.1 ± 17.4 ± 17.3 ± 17.5
Cortex ipsib (D1) 48.9 35.0 43.8 33.6
± 3.9 ± 3.3 ± 4.6 ± 3.0
Cortex contrab (D1) 44.1 33.7 41.0 32.6
± 10.4 ± 5.8 ± 10.0 ± 5.7
Hemisphere ipsi (D50) 37.4 32.5 34.2 30.7
± 23.1 ± 20.5 ± 22.8 ± 20.3
Hemisphere contra (D50) 21.1 17.5 19.4 16.5
± 13.1 ± 10.2 ± 12.9 ± 10.4
Eye ipsi (D1) 12.6 11.7 13.3 12.3
± 7.4 ± 6.8 ± 8.6 ± 7.3
Eye contra (D1) 11.2 10.3 10.3 10.3
± 6.9 ± 6.1 ± 6.3 ± 6.4
Lens ipsi (D1) 4.1 4.1 4.2 4.3
± 2.0 ± 2.2 ± 2.2 ± 2.2
Lens contra (D1) 3.7 3.6 3.5 3.4
± 1.9 ± 2.0 ± 2.0 ± 2.0
Optic nerve ipsi (D1) 36.1 33.5 34.8 31.7
± 21.0 ± 19.9 ± 20.1 ± 18.8
Optic nerve contra (D1) 27.1 23.4 25.8 22.2
± 15.5 ± 13.7 ± 15.7 ± 13.3
Cochlea ipsi (D50) 23.6 23.2 22.6 22.0
± 20.9 ± 20.8 ± 21.3 ± 21.1
Cochlea contra (D50) 9.2 8.7 8.4 7.9
± 9.8 ± 9.5 ± 9.5 ± 9.2
Hippocampus ipsi (D50) 43.0 41.4 41.5 40.4
± 22.3 ± 22.6 ± 22.5 ± 22.5
Hippocampus contra (D50) 30.7 27.0 29.2 25.8
± 12.8 ± 10.7 ± 12.4 ± 10.3
  1. Comparison of average median dose (D50) or the average near maximum dose (D1) in Gy plus minus one standard deviation to the target volume (TV) and OARs in robust and IMRT plans with and without cortex sparing. Some OARs are divided into ipsilateral (ispi) and contralateral (contra) hemisphere
  2. aTV: CTV for robust optimization, PTV for IMRT
  3. bCortex complies the technical OAR; CS Cortex sparing