Table 1 Comparison of characteristics of patients between nSCG and SCG
Characteristics | nSCG (450) n (%) | SCG (55) n (%) | P value | |
|---|---|---|---|---|
Age | Mean | 61 | 60 | 0.563 |
SD | 11 | 10 | ||
Gender | Male | 372 (82.7%) | 45 (81.8%) | 0.876 |
Female | 78 (17.3%) | 10 (18.2%) | ||
KPS Scorea | 90–100 | 116 (25.8%) | 19 (34.5%) | 0.165 |
60–80 | 334 (74.2%) | 36 (65.5%) | ||
Histology | Squamous | 266 (59.1%) | 28 (50.9%) | 0.244 |
Non-squamous | 184 (40.9%) | 27 (49.1%) | ||
Stages (AJCC 2002) | IIIA | 156 (34.7%) | 25 (45.5%) | 0.115 |
IIIB | 294 (65.3%) | 30 (54.5%) | ||
Smoking status | Never | 89 (19.8%) | 13 (23.6%) | 0.501 |
Former/current | 361 (80.2%) | 42 (76.4%) | ||
Weight lossb | ≥5 % | 121 (26.9%) | 15 (27.3%) | 0.959 |
<5 % | 328 (73.1%) | 40 (72.7%) | ||
Regimens | RT | 122 (27.1%) | 5 (9.1%) | 0.006 |
CRT | 147 (32.7%) | 18 (32.7%) | ||
CCRTc | 181 (40.2%) | 32 (58.2%) | ||
RT dose | <60Gy | 138 (30.7%) | 11 (20%) | 0.102 |
≥60Gy | 312 (69.3%) | 44 (80%) | ||
RT-technique | 2D–RT | 41 (9.1%) | 2 (3.6%) | 0.343 |
3D–CRT | 22 (4.9%) | 2 (3.6%) | ||
IMRT | 387 (86%) | 51 (92.7%) | ||
Response rated | CR + PR | 285 (64.2%) | 43 (78.2%) | 0.039 |
SD + PD | 159 (35.8%) | 12 (21.8%) | ||
Radiation esophagitise | <grade 2 | 269 (64.4%) | 37 (67.3%) | 0.670 |
≥grade 2 | 149 (35.6%) | 18 (32.7%) | ||
Radiation pneumonitisf | <grade 2 | 330 (85.3%) | 46 (83.6%) | 0.750 |
≥grade 2 | 57 (14.7%) | 9 (16.4%) | ||