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Table 3 Univariate analysis for patient’s characteristics and treatment factors

From: Clinical outcomes of retrograde intra-arterial chemotherapy concurrent with radiotherapy for elderly oral squamous cell carcinoma patients aged over 80 years old

Variables

Level

No of patients

Survival

Locoregional recurrence

   

HRb

95% CIc

P value

HR

95% CI

P value

Age

<83

20

1

 

0.495

1

 

0.438

 

≥83

11

1.333

0.334–11.875

 

2.098

0.776–18.226

 

Sex

Male

12

1

 

0.534

1

 

0.402

 

Female

19

1.785

0.287–11.128

 

2.561

0.284–23.047

 

ECOG-PS

0

25

1

 

0.091

1

 

0.026*

 

≥1

6

5.250

0.766–35.978

 

9.265

1.331–44.532

 

T classification

2 or 3

18

1

 

0.149

1

 

0.066

 

≥4a

13

2.258

0.745–6.839

 

4.084

0.911–18.303

 

N classification

0 or1

23

1

 

0.632

1

 

0.435

 

≥2b

8

1.240

0.513–2.996

 

2.223

0.298–16.559

 

Stage

II, III

12

1

 

0.237

1

 

0.083

 

≥IVA

19

2.075

0.618–6.968

 

7.147

0.776–56.792

 

Total dose of RTd

≥60 Gy

20

1

 

0.208

1

 

0.435

 

<60 Gy

11

0.233

0.024–2.252

 

1.575

0.987–25.154

 

Treatment delaya

No

19

1

 

0.264

1

 

0.044*

 

Yes

12

2.667

0.477–14.904

 

7.965

1.052–45.271

 
  1. *P < 0.05; aTreatment delay, more than 5 days; bhazard ratio; cconfidence interval; dradiotherapy