Fig. 4

TUG1 downregulation inhibits the HMGB1 expression in bladder cancer cell lines. a The expression of HMGB1 mRNA was detected by qRT-PCR analysis at 24 h after SW780 and BIU87 cells were transfected with si-NC or si-TUG1. b and c The protein level of HMGB1 was examined at 24 h after SW780 and BIU87 cells were transfected with si-NC or si-TUG1. *P < 0.05 vs. si-NC