Fig. 2
From: Influence of autophagy on the efficacy of radiotherapy
Title: In PI3K-Akt-mTOR signaling pathway, PI3K inhibits autophagy via activation of Akt. Akt promotes mTORC1 both directly and indirectly through inhibiting TSC complexes. mTORC1 directly inhibits autophagy as the final step. Legend: Green arrows represent activating or repressing processes for autophagy stimulation and red arrows represent activating or repressing processes for autophagy inhibition