Table 3 Complication grades and grade variations following salvage high-dose-rate brachytherapy (a, b) and stereotactic body radiation therapy (c, d) using CTCAE v4.03
a | ||||
HDRB | At baseline | Maximal acute toxicity | Maximal late toxicity | At last follow-up |
Urinary complication (n, %) | ||||
No complication | 5 (50.0) | - | 2 (20.0) | 2 (20.0) |
Grade 1 | 4 (40.0) | 2 (20.0) | - | 3 (30.0) |
Grade 2 | 1 (10.0) | 7 (70.0) | 6 (60.0) | 5 (50.0) |
Grade 3 | - | - | 1 (10.0) | - |
Grade 4 | - | - | - | - |
Not evaluated | 1 (10.0) | 1 (10.0) | - | |
Digestive complication (n, %) | ||||
No complication | 7 (70.0) | 8 (80.0) | 7 (70.0) | 10 (100.0) |
Grade 1 | 3 (30.0) | 1 (10.0) | 2 (20.0) | - |
Grade 2 | - | - | - | - |
Grade 3 | - | - | - | - |
Grade 4 | - | - | - | - |
Not evaluated | - | 1 (10.0) | 1 (10.0) | - |
b | ||||
HDRB | At 3 months | At last follow-up | ||
n | % | n | % | |
Urinary complication | ||||
No modification | 2 | 20.0 | 4 | 40.0 |
+ 1 grade | 3 | 30.0 | 5 | 50.0 |
+ 2 grades | 4 | 40.0 | 1 | 10.0 |
Not evaluated | 1 | 10.0 | - | - |
Digestive complication | ||||
No modification | 9 | 90.0% | 10 | 100 |
+ 1 grade | - | - | - | - |
+ 2 grades | - | - | - | - |
Not evaluated | 1 | 10.0% | - | - |
c | ||||
SBRT | At baseline | Maximal acute toxicity | Maximal late toxicity | At last follow-up |
Urinary complication (n, %) | ||||
No complication | 8 (44.4) | 2 (11.1) | 6 (33.3) | 4 (22.2) |
Grade 1 | 5 (27.8) | 5 (27.8) | 4 (22.2) | 6 (33.3) |
Grade 2 | 3 (16.7) | 2 (11.1) | 1 (5.6) | 3 (16.7) |
Grade 3 | 1 (5.6) | - | - | - |
Grade 4 | - | - | 1 (5.6) | - |
Not evaluated | 1 (5.6) | 9 (50.0) | 6 (33.3) | 5 (27.8) |
Digestive complication (n, %) | ||||
No complication | 13 (72.2) | 5 (27.8) | 9 (50.0) | 10 (55.6) |
Grade 1 | 1 (5.6) | 1 (5.6) | - | 1 (5.6) |
Grade 2 | 2 (11.1) | 2 (11.1) | 1 (5.6) | 2 (11.1) |
Grade 3 | - | - | - | - |
Grade 4 | - | - | - | - |
Not evaluated | 2 (11.1) | 10 (55.6) | 8 (44.4) | 5 (27.8) |
d | ||||
SBRT | At 3 months | At last follow-up | ||
n | % | n | % | |
Urinary complication | ||||
No modification | 4 | 22.3 | 12 | 66.7 |
+ 1 grade | 4 | 22.2 | 1 | 5.6 |
+ 2 grades | 1 | 5.6 | - | - |
Not evaluated | 9 | 50.0 | 5 | 27.8 |
Digestive complication | ||||
No modification | 7 | 38.9 | 12 | 66.7 |
+ 1 grade | - | - | - | - |
+ 2 grades | 1 | 5.6 | - | - |
Not evaluated | 10 | 55.6 | 6 | 33.3 |