|
Study Id
|
Q1
|
Q2
|
Q3
|
Q4
|
|---|
|
Cooperberg [39]
|
high
|
low
|
low
|
low
|
|
Bittner [27]
|
high
|
low
|
high
|
low
|
|
Buyyounouski [38]
|
low
|
low
|
low
|
low
|
|
Cooperberg (41)
|
low
|
high
|
low
|
low
|
|
Delouya [19]
|
low
|
high
|
low
|
low
|
|
Engineer [9]
|
low
|
high
|
low
|
low
|
|
Feng [28]
|
low
|
low
|
low
|
low
|
|
Frank [25]
|
unclear
|
high
|
low
|
low
|
|
Frank [45]
|
unclear
|
low
|
unclear
|
low
|
|
Halverson [46]
|
low
|
low
|
low
|
low
|
|
Huang [47]
|
low
|
low
|
low
|
low
|
|
Kaplan [12]
|
unclear
|
high
|
low
|
low
|
|
Krishnan [20]
|
low
|
high
|
low
|
low
|
|
Kubicek [48]
|
low
|
low
|
low
|
high
|
|
Marshall [11]
|
unclear
|
low
|
low
|
low
|
|
Potters [16]
|
unclear
|
high
|
low
|
low
|
|
Rodrigues [14]
|
high
|
unclear
|
low
|
low
|
|
Proust-Lima [51]
|
low
|
low
|
unclear
|
low
|
|
Sabolch [53]
|
low
|
low
|
low
|
low
|
|
Sanpaolo [21]
|
low
|
low
|
low
|
low
|
|
Slater [54]
|
high
|
low
|
low
|
low
|
|
Spratt [55]
|
low
|
low
|
low
|
low
|
|
Steigler [56]
|
low
|
low
|
low
|
unclear
|
|
Taylor [58]
|
low
|
low
|
unclear
|
low
|
|
Vainshtein [18]
|
low
|
low
|
low
|
low
|
|
Vance [60]
|
low
|
low
|
low
|
low
|
|
Wattson [61]
|
low
|
high
|
low
|
low
|
|
Westphalen [62]
|
unclear
|
high
|
low
|
low
|
|
Williams [17]
|
low
|
high
|
low
|
low
|
|
Yoshida [15]
|
unclear
|
low
|
unclear
|
low
|
|
Zaorsky [65]
|
low
|
low
|
low
|
low
|
|
Zelefsky [10]
|
low
|
high
|
low
|
low
|
|
Zelefsky [68]
|
low
|
low
|
low
|
low
|
|
Zelefsky [66]
|
low
|
low
|
low
|
low
|
|
Zumsteg [69]
|
low
|
low
|
low
|
low
|
|
D’Amico [43]
|
low
|
high
|
low
|
low
|
|
Yu [64]
|
low
|
low
|
low
|
low
|
|
D’Ambrosio [41]
|
unclear
|
low
|
low
|
low
|
|
Denham [44]
|
low
|
unclear
|
low
|
low
|
|
McKenna [49]
|
unclear
|
high
|
low
|
high
|
|
Yu [63]
|
low
|
unclear
|
unclear
|
low
|
|
D’Amico [42]
|
low
|
low
|
low
|
low
|
|
Zelefsky [67]
|
low
|
low
|
low
|
low
|
|
Thames [59]
|
low
|
low
|
unclear
|
low
|
|
Qian [52]
|
low
|
low
|
low
|
low
|
|
Sylvester [57]
|
low
|
low
|
low
|
high
|
|
Murgic [50]
|
low
|
high
|
low
|
low
|
|
Low/47
|
34 (72%)
|
30 (64%)
|
40 (85%)
|
43 (91%)
|
- Q1: Was the defined representative sample of patients assembled at a common (usually early) point in the course of their disease)? Q2: Was patient follow-up sufficiently long and complete? Q3: Were outcome criteria either objective or applied in a ‘blind’ fashion? Q4: If subgroups with different prognoses are identified, did adjustment for important prognostic factors take place?
- High = high risk of bias, low = low risk of bias, unclear = unclear if study design is at high or low risk of bias
