Rodrigues [14]
|
Survival model (Cox)
|
T stage, PSA and Gleason
|
Yes
|
Internal (cross validation)
|
0.64
|
c-index
|
7839 (NR)
|
OS
|
Brachytherapy and or EBRT
|
Rodrigues [14]
|
Survival model (Cox)
|
T stage, PSA and Gleason
|
Yes
|
Internal (cross validation)
|
0.67
|
c-index
|
7839 (NR)
|
BFFF
|
Brachytherapy and or EBRT
|
Delouya [19]
|
Survival model (Cox)
|
CAPRA score (Age, PSA, Gleason score, T-stage, PPB)
|
Yes
|
External
|
0.69, 95%CI 55.0 to 83.8; 0.66, 95%CI 54.4 to 78.3; 0.68, 95%CI 58.5 to 77.2; 0.62 95%CI 53.2 to 70.7
|
c-index at 2, 3, 4, and 5 years
|
744 (47)
|
BFFF
|
Brachytherapy or EBRT
|
Delouya [19]
|
Survival model (Cox)
|
D’Amico classification (T-stage, PSA and Gleason)
|
Yes
|
External
|
59.1% - 61.6%; and 54.5% - 61.6%
|
3-5 year sensitivity and specificity
|
744 (47)
|
BFFF
|
Brachytherapy or EBRT
|
Wattson [61]
|
Survival Model (Fine and Gray)
|
Number of high-risk factors (prostate-specific antigen >20 ng/mL, biopsy Gleason score 8–10, or clinical stage T2c), adjusted for age, comorbidity, and the type of supplemental treatment
|
No, comorbidity
|
Not stated
|
Not stated
|
NA
|
2234 (57)
|
PCSM
|
EBRT and or Brachytherapy
|
Kubicek [48]
|
Survival model
|
Mid therapy PSA (<25% vs > =25%)
|
No, mid therapy PSA cohort specific
|
Not stated
|
Not stated
|
NA
|
717 (NR)
|
Disease free survival
|
Brachytherapy and EBRT
|
Kubicek [48]
|
Survival model
|
Mid therapy PSA (<25% vs > =25%)
|
No, mid therapy PSA cohort specific
|
Not stated
|
Not stated
|
NA
|
717 (NR)
|
OS
|
Brachytherapy and EBRT
|
Krishnan [20]
|
Survival model (Cox)
|
CAPRA scores (based on PSA, Biopsy Gleason, Age at diagnosis, clinical tumour stage and % biopsy cores positive for cancer)
|
Yes
|
External
|
Not stated
|
NA
|
345 (45)
|
BCF
|
EBRT and/or LDR
|
McKenna [49]
|
Survival model (Cox)
|
Patient age, hormonal treatment, baseline PSA, and degree of extracapsular extension, pre-treatment MRI
|
Yes, where MRI is routine
|
Not stated
|
Not stated
|
NA
|
80 (4)
|
Metastatic recurrence and BCF
|
EBRT or EBRT with Brachytherapy
|