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Table 2 The physical constraints used in DVO

From: An integrated strategy of biological and physical constraints in biological optimization for cervical carcinoma

Structures Constraints Parameters
PTV Min dose 54 Gy
Dose/volume V97 > 54.5 Gy
Dose/volume V3 < 57.5 Gy
Max dose 58 Gy
OAR Rectum Dose/volume V40 < 35 Gy, and two extra dose/volume constraints for reducing the mean dose
Bladder Dose/volume V40 < 35 Gy, and two extra dose/volume constraints for reducing the mean dose
Femur-heads Dose/volume V5 < 35Gy, and two extra dose/volume constraints for reducing the mean dose
B-Pa Max dose 50 Gy
  1. aThe assistance organ Body-PTV (B-P) was defined as the body volume in the CT data set minus the PTV leaving a 0.3 cm gap