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Table 1 Univariate analysis of overall survival

From: Definitive salvage radiation therapy and chemoradiation therapy for lymph node oligo-recurrence of esophageal cancer: a Japanese multi-institutional study of 237 patients

Factors

No.

MST

95% CI

p value

Age, y

  > 66

109

21.5

15.3–32.6

0.76

  ≤ 66

128

21.6

14.6–29.1

 

Serum SCC antibody

  > 2 ng/mL

65

23.0

10.0–29.0

0.42

  ≤ 2 ng/mL

172

21.6

18.0–30.6

 

Combined CTX

 Without

38

10.8

6.3–21.5

0.000055

 With

199

26.0

18.5–32.8

 

DFI

  ≤ 12 mo

119

14.5

12.8–18.8

0.0013

  > 12 months

118

30.6

23.2–42.0

 

DFI

  ≤ 24 months

183

18.0

14.2–23.2

0.0041

  > 24 months

54

41.0

26.0–116.0

 

KPS

  < 90%

83

14.6

12.3–28.0

0.11

  ≥ 90%

154

26.0

18.0–32.8

 

No. of LN metastasis

 Mono

165

26.0

17.8–33.0

0.44

 Multiple

72

18.8

14.6–28.5

 

LN max diameter

  > 22 mm

109

15.7

13.5–23.5

0.0052

  ≤ 22 mm

128

29.1

19.8–41.1

 

LN location

 Distant

90

20.2

14.2–27.0

0.41

 Locoregional

147

26.4

18.0–34.3

 

Histopathology

 SCC

231

23.0

18.0–28.5

0.55

 Others

6

15.0

12.0-NA

 
  1. Abbreviation: No. number, MST median survival time, CI confidence interval, SCC squamous cell carcinoma, CTX chemotherapy, DFI disease-free interval, KPS Karnofsky performance status, LN lymph node