Table 2 Dose parameters for the PTVs and OARs for all four techniques
HTF | HTF – HTF hh p-value | HTF hh | HTF hh – IMRT p-value | IMRT | IMRT – VMAT p-value | VMAT | HTF hh – VMAT p-value | |
|---|---|---|---|---|---|---|---|---|
PTVp V90% (%) | 99.9 (99.7–100) | ≤0.01 | 99.5 (95.6–100) | 0.08 | 99.8 (99.2–100) | ≤0.01 | 99.5 (98.8–99.9) | 0.08 |
PTVp V95% (%) | 97.8 (97.2–99.5) | 0.02 | 97.2 (91.8–99.5) | 0.65 | 97.3 (96.7–98.8) | 0.09 | 97.1 (96.6–97.4) | 0.14 |
PTVn V90% (%) | 97.9 (96.6–99.3) | ≤0.01 | 89.4 (73.3–98.7) | ≤0.01 | 98.2 (91.3–99.9) | 0.51 | 99.5 (98.2–99.9) | ≤0.01 |
PTVn V95% (%) | 86.5 (81.4–94.2) | ≤0.01 | 73.6 (56.9–87.6) | ≤0.01 | 91.1 (77.8–98.2) | 0.05 | 95.4 (88.3–98.3) | ≤0.01 |
CI95% | 1.24 (1.04–1.41) | ≤0.01 | 1.16 (1.01–1.29) | ≤0.01 | 1.06 (0.93–1.18) | ≤0.01 | 0.90 (0.77–1.06) | ≤0.01 |
CI90% | 1.49 (1.25–1.66) | ≤0.01 | 1.41 (1.22–1.51) | ≤0.01 | 1.33 (1.14–1.41) | ≤0.01 | 1.09 (0.97–1.25) | ≤0.01 |
Lungs Dmean (Gy) | 4.8 (3.9–6.1) | 0.02 | 4.7 (3.9–6.1) | 0.33 | 4.8 (3.8–5.9) | 0.24 | 5.2 (4.2–6.8) | 0.17 |
Heart Dmean (Gy) | 3.3 (1.7–6.2) | ≤0.01 | 3.3 (1.6–6.1) | ≤0.01 | 2.9 (1.6–5.7) | 0.04 | 3.6 (2.0–5.7) | 0.51 |
Contralat. breast Dmean (Gy) | 0.7 (0.3–0.9) | ≤0.01 | 0.6 (0.3–0.9) | 0.02 | 0.6 (0.3–0.7) | ≤0.01 | 2.3 (0.6–4.2) | ≤0.01 |
hh+10 V40Gy (cc) | 20.7 (0–66.9) | ≤0.01 | 0.5 (0–1.2) | 0.37 | 0.6 (0–1.8) | 0.31 | 0.6 (0–1.3) | 0.26 |