Table 2 Treatment Parameters

Concurrent chemotherapy

3 patients vinorelbin

4 patients capecitabin

1 patient sunitinib

1 patient doxorubicin

1 patient vinorelbin

1 patient capecitabin

 a) Ipsilateral chest wall

2 patients

2patients

 b) More than 1/2 of the thoracic circumference plus loco-regional lymph nodes

4 patients

9 patients

 c) More than 2/3 of the thoracic circumference plus loco-regional lymph nodes

6 patients

3 patients

 d) Extranodal metastasis within the PTV

1 patient (pleura)

2 patients (bone lesions)

 e) Extensive skin metastases

4 patients

PTV volume (cm³)

2984 (1457–6837)

1330 (520–6623)

Cranio-caudal PTV extension (cm)

30 (19–52)

28 (18,2–43,5)

Median total dose

40 Gy (32–60 Gy)

50 Gy (40–60 Gy)

Median dose per fraction

2 Gy (1,8–3,0 Gy)

2,0 Gy (1,5–2,24 Gy)

Simultaneous integrated boost

2 patients (50.4/56 Gy with single doses of 1.8/2.0Gy;

55,8/60,1 Gy with single doses of 1.8/1.94 Gy)

3 patients (45/50 Gy with single doses of 1.8/2.0 Gy;

45/50/56 Gy with single doses of 1.8/2.0/2.24 Gy;

46Gy/50 with single doses of 2.0/2.17 Gy)

Neutron boost

6 patients (4.6–12Gy)

−