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Table 2 Average MLD (Gy) and V20 (%) of gated and ITV plans as well as difference between the two (ITV-Gating) for 3 × 18 Gy fractionation. Ranges are given in parentheses. The V20 limit taken from RTOG 0236 is provided in brackets

From: To gate or not to gate - dosimetric evaluation comparing Gated vs. ITV-based methodologies in stereotactic ablative body radiotherapy (SABR) treatment of lung cancer

  MLD (Gy) V20 (%) [Limit: 10 %]
Gating ITV Difference Gating ITV Difference
Peripheral-Lung Wall 2.94 ± 1.35 (0.69, 5.67) 3.10 ± 1.47 (0.83, 6.79) 0.16 ± 0.64 (−1.38, 2.82) 3.73 ± 2.24 (0.14, 8.89) 3.94 ± 2.24 (0.54, 8.32) 0.20 ± 1.17 (−4.54, 4.52)
Peripheral-Island 3.35 ± 1.16 (1.16, 6.05) 3.45 ± 1.18 (1.13, 6.16) 0.10 ± 0.56 (−1.72, 1.75) 4.40 ± 2.12 (0.95, 9.55) 4.59 ± 2.22 (1.27, 10.82) 0.20 ± 1.02 (−2.95, 3.01)
Central 4.05 ± 1.63 (1.06, 7.59) 4.15 ± 1.62 (1.19, 8.31) 0.10 ± 0.64 (−1.50, 2.52) 5.90 ± 3.61 (1.53, 14.96) 5.92 ± 3.37 (1.03, 16.93) 0.02 ± 1.30 (−3.54, 3.68)
LL 3.29 ± 1.43 (0.69, 7.59) 3.73 ± 1.56 (0.83, 8.31) 0.40 ± 0.55 (−0.59, 2.52) 4.27 ± 2.89 (0.14, 14.96) 4.93 ± 2.98 (0.58, 16.93) 0.66 ± 0.95 (−1.29, 3.68)
ML 3.10 ± 0.81 (2.02, 4.23) 3.33 ± 1.40 (1.79, 6.79) 0.23 ± 1.06 (−0.98, 2.82) 3.48 ± 1.14 (1.70, 5.03) 3.83 ± 2.01 (1.64, 8.32) 0.35 ± 1.72 (−1.71, 4.52)
UL 3.44 ± 1.44 (0.90, 7.11) 3.34 ± 1.41 (0.87, 6.60) −0.11 ± 0.44 (−1.72, 1.12) 4.80 ± 2.64 (0.48, 14.00) 4.59 ± 2.43 (0.54, 12.45) −0.24 ± 0.91 (−4.54, 3.05)