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Table 1 Comparison of plan quality

From: Simultaneous integrated boost (SIB) radiation therapy of right sided breast cancer with and without flattening filter - A treatment planning study

Parameter

Goal

IMRT FF

IMRT FFF

VMAT FF

VMAT FFF

tVMAT FF

tVMAT FFF

SIBm5

V95%

>95

97.2 ± 1.2

97.5 ± 1.3

98.2 ± 1.0

98.7 ± 0.8

95.5 ± 2.2

95.7 ± 2.0

 

D98%

 

59.6 ± 0.4

59.7 ± 0.4

60.0 ± 0.5

60.2 ± 0.4

59.0 ± 0.7

59.1 ± 0.6

 

D02%

 

65.6 ± 0.4

65.6 ± 0.2

65.5 ± 0.4

65.3 ± 0.4

66.1 ± 0.4

66.1 ± 0.5

 

HI

 

9.6 ± 1.2

9.3 ± 0.9

8.8 ± 1.2

8.2 ± 0.9

11.3 ± 1.4

11.1 ± 1.5

 

CI

>0.7

0.77 ± 0.05

0.78 ± 0.05

0.78 ± 0.05

0.78 ± 0.05

0.75 ± 0.05

0.75 ± 0.05

PTVm5

V95%

>95

96.8 ± 2.3

96.8 ± 1.9

97.6 ± 1.5

98.3 ± 0.7

95.2 ± 4.3

94.9 ± 3.8

 

CI

>0.7

0.77 ± 0.05

0.77 ± 0.06

0.77 ± 0.05

0.78 ± 0.05

0.75 ± 0.04

0.76 ± 0.04

PTV (excluding SIB)

D98%

 

46.9 ± 0.7

46.9 ± 0.6

46.9 ± 1.1

47.4 ± 0.6

45.7 ± 2.0

45.5 ± 2.0

 

D02%

 

55.2 ± 0.5

55.1 ± 0.3

55.4 ± 0.4

55.4 ± 0.4

56.1 ± 0.7

56.1 ± 0.7

 

HI

 

16.4 ± 1.6

16.3 ± 1.1

16.9 ± 2.2

15.8 ± 1.1

20.4 ± 4.5

20.9 ± 4.6

Lung ipsilateral

V20Gy

<15

13.2 ± 3.8

13.1 ± 3.6

13.1 ± 3.3

13.5 ± 3.3

13.8 ± 3.1

14.1 ± 3.0

 

Dmean

<12

8.7 ± 1.3

8.7 ± 1.3

8.7 ± 1.2

8.9 ± 1.2

8.9 ± 1.0

8.9 ± 1.0

Lung contralateral

V5Gy

<5

0.2 ± 0.4

0.4 ± 0.4

0.1 ± 0.2

0.3 ± 0.3

0.0 ± 0.0

0.0 ± 0.0

 

Dmean

<3

1.6 ± 0.4

1.7 ± 0.2

1.7 ± 0.2

1.8 ± 0.2

1.0 ± 0.1

0.7 ± 0.1

Breast contralateral

Dmean

<3

1.8 ± 0.4

1.9 ± 0.4

1.8 ± 0.3

1.8 ± 0.4

1.3 ± 0.2

1.0 ± 0.2

 

D02%

 

5.4 ± 1.3

5.6 ± 1.2

4.5 ± 1.0

4.8 ± 1.2

3.2 ± 0.6

2.8 ± 0.8

Heart

Dmean

<5

2.4 ± 0.5

2.6 ± 0.4

2.7 ± 0.5

2.6 ± 0.5

1.7 ± 0.3

1.4 ± 0.2

 

D02%

 

5.0 ± 1.1

5.7 ± 0.9

5.0 ± 1.0

5.1 ± 0.9

3.3 ± 0.5

3.0 ± 0.6

Normal Tissue

Dmean

 

4.4 ± 0.4

4.6 ± 0.3

4.4 ± 0.4

4.4 ± 0.3

3.8 ± 0.3

3.6 ± 0.3

 

D02%

 

42.5 ± 1.1

42.2 ± 1.3

41.9 ± 1.7

41.9 ± 1.3

41.9 ± 2.2

41.5 ± 1.9

  1. Mean values and standard deviation of the dose volume parameters for FF and FFF mode averaged over all patients separated by the treatment technique. Dose values are given in Gy, volumes in % of the structure volume. HI stands for homogeneity index (values are reported in %), CI for conformity index. Bold values indicate statistically significant superior values in the comparison of FF vs FFF. Bold-italic letters indicate best values in the comparison of all planning techniques and irradiation modes