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Table 1 Comparison of plan quality

From: Simultaneous integrated boost (SIB) radiation therapy of right sided breast cancer with and without flattening filter - A treatment planning study

Parameter Goal IMRT FF IMRT FFF VMAT FF VMAT FFF tVMAT FF tVMAT FFF
SIBm5 V95% >95 97.2 ± 1.2 97.5 ± 1.3 98.2 ± 1.0 98.7 ± 0.8 95.5 ± 2.2 95.7 ± 2.0
  D98%   59.6 ± 0.4 59.7 ± 0.4 60.0 ± 0.5 60.2 ± 0.4 59.0 ± 0.7 59.1 ± 0.6
  D02%   65.6 ± 0.4 65.6 ± 0.2 65.5 ± 0.4 65.3 ± 0.4 66.1 ± 0.4 66.1 ± 0.5
  HI   9.6 ± 1.2 9.3 ± 0.9 8.8 ± 1.2 8.2 ± 0.9 11.3 ± 1.4 11.1 ± 1.5
  CI >0.7 0.77 ± 0.05 0.78 ± 0.05 0.78 ± 0.05 0.78 ± 0.05 0.75 ± 0.05 0.75 ± 0.05
PTVm5 V95% >95 96.8 ± 2.3 96.8 ± 1.9 97.6 ± 1.5 98.3 ± 0.7 95.2 ± 4.3 94.9 ± 3.8
  CI >0.7 0.77 ± 0.05 0.77 ± 0.06 0.77 ± 0.05 0.78 ± 0.05 0.75 ± 0.04 0.76 ± 0.04
PTV (excluding SIB) D98%   46.9 ± 0.7 46.9 ± 0.6 46.9 ± 1.1 47.4 ± 0.6 45.7 ± 2.0 45.5 ± 2.0
  D02%   55.2 ± 0.5 55.1 ± 0.3 55.4 ± 0.4 55.4 ± 0.4 56.1 ± 0.7 56.1 ± 0.7
  HI   16.4 ± 1.6 16.3 ± 1.1 16.9 ± 2.2 15.8 ± 1.1 20.4 ± 4.5 20.9 ± 4.6
Lung ipsilateral V20Gy <15 13.2 ± 3.8 13.1 ± 3.6 13.1 ± 3.3 13.5 ± 3.3 13.8 ± 3.1 14.1 ± 3.0
  Dmean <12 8.7 ± 1.3 8.7 ± 1.3 8.7 ± 1.2 8.9 ± 1.2 8.9 ± 1.0 8.9 ± 1.0
Lung contralateral V5Gy <5 0.2 ± 0.4 0.4 ± 0.4 0.1 ± 0.2 0.3 ± 0.3 0.0 ± 0.0 0.0 ± 0.0
  Dmean <3 1.6 ± 0.4 1.7 ± 0.2 1.7 ± 0.2 1.8 ± 0.2 1.0 ± 0.1 0.7 ± 0.1
Breast contralateral Dmean <3 1.8 ± 0.4 1.9 ± 0.4 1.8 ± 0.3 1.8 ± 0.4 1.3 ± 0.2 1.0 ± 0.2
  D02%   5.4 ± 1.3 5.6 ± 1.2 4.5 ± 1.0 4.8 ± 1.2 3.2 ± 0.6 2.8 ± 0.8
Heart Dmean <5 2.4 ± 0.5 2.6 ± 0.4 2.7 ± 0.5 2.6 ± 0.5 1.7 ± 0.3 1.4 ± 0.2
  D02%   5.0 ± 1.1 5.7 ± 0.9 5.0 ± 1.0 5.1 ± 0.9 3.3 ± 0.5 3.0 ± 0.6
Normal Tissue Dmean   4.4 ± 0.4 4.6 ± 0.3 4.4 ± 0.4 4.4 ± 0.3 3.8 ± 0.3 3.6 ± 0.3
  D02%   42.5 ± 1.1 42.2 ± 1.3 41.9 ± 1.7 41.9 ± 1.3 41.9 ± 2.2 41.5 ± 1.9
  1. Mean values and standard deviation of the dose volume parameters for FF and FFF mode averaged over all patients separated by the treatment technique. Dose values are given in Gy, volumes in % of the structure volume. HI stands for homogeneity index (values are reported in %), CI for conformity index. Bold values indicate statistically significant superior values in the comparison of FF vs FFF. Bold-italic letters indicate best values in the comparison of all planning techniques and irradiation modes