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Fig. 9 | Radiation Oncology

Fig. 9

From: Temporo-spatial cell-cycle kinetics in HeLa cells irradiated by Ir-192 high dose-rate remote afterloading system (HDR-RALS)

Fig. 9

Response to irradiation under hypoxic conditions. a Pedigree analysis of cells irradiated in green or red phase at 5 or 20 mm under hypoxia, analyzed separately. Green bars: green phase in Fucci; red bars: red phase in Fucci; yellow bars: cells abnormally expressing red and green fluorescence at mitosis. b FGPD of cells irradiated under hypoxia at 5 or 20 mm. Data for cells irradiated under normoxia were derived from Fig. 5a for comparison. Data are represented as box-and-whisker plots, as described in Fig. 7b. Norm, cells irradiated under normoxia; Hyp, cells irradiated under hypoxia. *, P < 0.05; **. P < 0.01. c FGPD of cells irradiated in green or red phase under hypoxia at 5 or 20 mm. Data for cells irradiated under normoxia were derived from Fig. 7b for comparison. Data are represented as box-and-whisker plots, as described in Fig. 7b. Norm, cells irradiated under normoxia; Hyp, cells irradiated under hypoxia. *, P < 0.05; **. P < 0.01; N.S., not significant

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