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Table 3 Summary of OAR doses (hippocampus and normal brain tissue excluded)

From: Non-coplanar volumetric-modulated arc therapy (VMAT) for craniopharyngiomas reduces radiation doses to the bilateral hippocampus: a planning study comparing dynamic conformal arc therapy, coplanar VMAT, and non-coplanar VMAT

Structure/index

DCAT

coVMAT

ncVMAT

P-value (ANOVA)

P-value (DCAT vs. coVMAT)

P-value (DCAT vs. ncVMAT)

P-value (coVMAT vs. ncVMAT)

(Mean ± SD)

Lt. optic nerve

       

  D2%

38.4 ± 11.9

37.2 ± 11.2

36.2 ± 12.8

0.915

   

Rt. optic nerve

       

  D2%

43.6 ± 9.5

40.5 ± 10.9

41.4 ± 10.5

0.789

   

Chiasm

       

  D2%

53.3 ± 0.8

52.2 ± 0.9

52.4 ± 0.7

<0.05

<0.05

<0.05

1

Lt. lens

       

  D2%

3.2 ± 0.7

2.2 ± 0.7

1.9 ± 0.4

<0.05

<0.05

<0.05

0.854

Rt. lens

       

  D2%

3.2 ± 0.7

2.3 ± 0.7

1.8 ± 0.5

<0.05

<0.05

<0.05

0.224

  1. If a significant difference was evident when data from the entire cohort were compared via two-way analysis of variance (ANOVA), the Bonferroni post hoc test was performed to compare pairs of modalities
  2. D2% dose to 2 % of the volume
  3. SD standard deviation, DCAT dynamic conformal arc therapy, coVMAT coplanar volumetric-modulated arc therapy, ncVMAT noncoplanar volumetric-modulated arc therapy, Lt. left, Rt. right
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Radiation Oncology

ISSN: 1748-717X

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