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Table 1 Patient, tumor, and treatment characteristics at initial planning (CT0)

From: A Nomogram to predict parotid gland overdose in head and neck IMRT

ID

Gender

Age

TNM

Tumor sublocation

Chemotherapy

Volume (cm3)

Mean planned PG dose (Gy)

Xerostomia NTCP (%) [23, 24]

CTV70

ILP

CLP

ILP

CLP

ILP

CLP

1

M

77

T4N0

Tonsil

Cetuximab

45.2

52.1

48.6

30.2

31.1

27.1

28.9

2

F

61

T2N2

Base of tongue

CDDP

26.3

31.1

27.5

31.4

26

29.7

19.1

3

M

70

T3N2c

Oropharynx

CDDP

181.5

24.9

20.7

37.9

31.1

45.1

29.1

4

F

66

T2N2c

Oropharynx

Cetuximab

107.2

27.8

23.4

32.9

27.9

33.1

22.5

5

M

57

T3N0

Velum

CDDP

62.4

20.7

18

28.1

27.8

23

22.3

6

M

67

T3N2c

Base of tongue

CDDP

156.2

24.5

22.7

30.8

29.4

25.4

22.1

7

M

52

T4N2a

Tonsil

Cetuximab

165.1

N/A

21.6

N/A

28.7

N/A

24

8

M

67

T4N1

Base of tongue

CDDP

139.3

22

19.3

30.7

29.2

28

25

9

F

65

T3N3

Base of tongue

CDDP

237.5

23.9

20.2

42.4

31.1

56.1

29

10

F

65

T4N3

Oropharynx

CDDP

257.9

N/A

24.5

N/A

35.2

N/A

38.5

11

M

50

T4N2c

Oropharynx

CDDP

434.5

N/A

17.7

N/A

36.3

N/A

41.1

12

M

53

T3N0

Base of tongue

CDDP

14.4

16.6

23.3

41.3

24.2

53.6

16.3

13

M

73

T3N2c

Oropharynx

Cetuximab

147

29.4

29.2

54.6

32.2

82.1

31.4

14

M

56

T3N0

Epiglottic

Cetuximab

14

22.8

29.2

19.7

9.2

10.3

2.7

15

M

75

T2N2a

Oropharynx

Cetuximab

76.3

20.3

22.4

29.4

29.1

25.6

25

16

M

57

T3N0

Oropharynx

CDDP

46.5

23.8

31.2

32.1

31.2

29.3

31.3

17

M

64

T3N2c

Epiglottic

CDDP

109.8

23.5

15.6

39.6

17.3

49.3

7.8

18

M

55

T1N2b

Tonsil

CDDP

31

20.2

20.8

25.7

23.63

18.7

15.3

19

M

65

T4N0

Velum

CDDP

10.1

23.7

25.3

28.6

28.2

24

23.2

20

M

56

T4N2b

Pharyngeal wall

CDDP

150

32.4

26.8

45

24.4

62.8

16.6

  1. M male, F female, CTV70 clinical target volume receiving 70Gy, ILP ipsilateral parotid glands, CLP contralateral parotid glands, CDDP cisplatin, NTCP normal tissue complication, PG parotid gland, N/A not applicable (PGs included in the CTV)
  2. The NTCP Lyman Kutcher Burman (LKB) model (n = 1, m = 0.4, and median toxic dose [TD50] = 39.9) [23, 24] defined the risk of xerostomia as a salivary flow ratio <25 % of the pretreatment one