Fig. 4

Univariate analysis. Subgroup analysis based on the dichotomization of MTV and SUVmean at the sample median. In green group B + C: Patients with MTV above the median + patients with mean SUV below the median. In red group A + C: Patients with MTV below the median + patients with mean SUV below the median. In orange group A + D: Patients with MTV below the median + patients with mean SUV above the median. In blue group B + D: Patients with MTV above the median + patients with mean SUV above the median. a) Overall survival: B + C 87 %, A + C 83 %, A + D 68 %, B + D 0 %; p < 0.003. b) Disease-free survival: B + C 90 %, A + C 83 %, A + D 50 %, B + D 25 %; p < 0.0003. c) Locoregional control: B + C 90 %, A + C 83 %, A + D 78 %, B + D 50 %; p < 0.03