Table 3 Biological cost function parameters used in this study

Structure

Endpoint

D₅₀ (Gy)

α/β (Gy)

n

m

References

BilatLung-ITV

Pneumonit-is Grade ≥ 2

30.8

1.3

0.99

0.37

[36, 38]

Esophagus

Esophagitis Grade ≥ 2

51.0

10

0.44

0.32

[50]

Heart

Pericarditis

60.6

2.5

0.64

0.13

[51]

Structure

Endpoint

D₅₀ (Gy)

α/β (Gy)

ɣ

s

Reference

Spinal cord

Myelitis necrosis

68.6

3

1.9

4.0

[52]

Esophagus

Clinical Stricture

68.6

3

2.8

3.4

[52]