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Table 2 A summary of hippocampal dosimetric parameters used in this study

From: Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study

 

Bilateral hippocampi

Left hippocampus

Right hippocampus

 

Mean (95 % CI)

Median

Mean (95 % CI)

Median

Mean (95 % CI)

Median

Volume (c.c.)

4.99 (4.59–5.40)

5.18

2.41 (2.20–2.62)

2.41

2.58 (2.37–2.79)

2.71

Maximum EQD2 (Gy)

13.51 (11.85–15.17)

12.64

13.20 (11.50–14.9)

12.41

12.93 (11.64–14.22)

12.64

D20% EQD2 (Gy)

8.30 (7.81–8.78)

8.26

8.34 (7.86–8.82)

8.22

8.27 (7.78–8.76)

8.28

D40% EQD2 (Gy)

7.65 (7.19–8.11)

7.68

7.67 (7.22–8.12)

7.70

7.63 (7.16–8.10)

7.70

D50% EQD2 (Gy)

7.40 (6.96–7.85)

7.45

7.41 (6.97–7.85)

7.48

7.37 (6.92–7.82)

7.47

D80% EQD2 (Gy)

6.70 (6.32–7.07)

6.80

6.72 (6.35–7.09)

6.73

6.69 (6.30–7.07)

6.84

Minimum EQD2 (Gy)

5.78 (5.51–6.04)

5.82

5.61 (5.04–6.18)

5.73

5.86 (5.58–6.14)

5.90

  1. Abbreviations: D 10% biologically equivalent dose in 2-Gy fractions (EQD2) assuming α/β = 2Gy to 10 % of the hippocampus volume of interest (left, right, or bilateral); therefore, Dm% is defined as the EQD2 to m% of the hippocampal volume of interest; D100% = the EQD2 to 100 % of the structure volume, corresponding to the minimal dose received by the hippocampus of interest in our study; Maximum the maximal EQD2 irradiating the hippocampus volume of interest
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Radiation Oncology

ISSN: 1748-717X

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