PFS | CSS | OS | ||||
---|---|---|---|---|---|---|
Characteristics | HR (95 % CI) | P-value | HR (95 % CI) | P-value | HR (95 % CI) | P-value |
Age | 0.42 | 0.32 | 0.96 | |||
<75 | 1 | 1 | 1 | |||
≥75 | 0.82 (0.51-1.33) | 0.70 (0.34-1.42) | 1.01 (0.62-1.66) | |||
Sex | 0.66 | 0.81 | 0.86 | |||
M | 1 | 1 | 1 | |||
F | 0.83 (0.35-1.94) | 0.86 (0.24-3.08) | 1.08 (0.45-2.58) | |||
ECOG PS | 0.27 | 0.14 | 0.90 | |||
0-1 | 1 | 1 | 1 | |||
2-3 | 1.33 (0.80-2.19) | 1.66 (0.84-3.27) | 1.56 (0.93-2.60) | |||
aFEV1(%) | 0.63 | 0.96 | 0.42 | |||
≥70 | 1 | 1 | 1 | |||
<70 | 0.88 (0.54-1.45) | 1.02 (0.52-2.00) | 0.81 (0.49-1.34) | |||
Pathology | ||||||
Squamous cell carcinoma | 1 | 1 | 1 | |||
Adenocarcinoma | 1.25 (0.56-2.79) | 0.59 | 1.63 (0.62-4.29) | 0.32 | 1.32 (0.60-2.91) | 0.49 |
Others | 0.93 (0.35-2.48) | 0.88 | 0.70 (0.17-2.92) | 0.63 | 0.78 (0.28-2.16) | 0.64 |
Tumor size | 0.11 | 0.50 | 0.20 | |||
<7 c m | 1 | 1 | 1 | |||
≥7 c m | 0.60 (0.32-1.11) | 0.75 (0.33-1.72) | 0.65 (0.34-1.25) | |||
T-stage | 0.02 | 0.12 | 0.08 | |||
1-2 | 1 | 1 | 1 | |||
3-4 | 2.00 (1.11-3.61) | 1.90 (0.85-4.26) | 1.67 (0.93-2.98) | |||
N-stage | 0.18 | 0.30 | 0.29 | |||
0-1 | 1 | 1 | 1 | |||
2-3 | 1.42 (0.85-2.39) | 1.46 (0.72-2.97) | 1.33 (0.79-2.26) | |||
Initial response | 0.02 | 0.02 | 0.07 | |||
CR or PR | 1 | 1 | 1 | |||
SD or PD | 2.03 (1.15-3.58) | 2.40 (1.16-4.98) | 1.68 (0.96-2.94) |