Variable | No. of cohorts | Cases/Total | OR [95Â % CI]a | P z-test | I 2 (%) | P het | Power (%) |
---|---|---|---|---|---|---|---|
rs13181 | |||||||
Dominant model | 9 | 342/1486 | 0.71 [0.55, 0.93] | 0.01 | 0 | 0.59 | 79.2 |
 Early adverse effect | 8 | 325/1417 | 0.72 [0.55, 0.94] | 0.02 | 0 | 0.49 | 73.8 |
 Acute skin toxicity | 4 | 219/895 | 0.85 [0.61, 1.20] | 0.36 | 0 | 0.43 | 18.0 |
 Acute esophageal toxicity | 2 | 70/273 | 0.56 [0.32, 0.97] | 0.04 | 0 | 0.49 | 54.6 |
 Acute gastrointestinal toxicity | 2 | 36/249 | 0.44 [0.19, 1.02] | 0.06 | 0 | 0.87 | 52.7 |
Recessive model | 5 | 286/1090 | 0.75 [0.50, 1.12] | 0.16 | 43 | 0.14 | 27.4 |
Allelic model | 5 | 286/1090 | 0.78 [0.64, 0.97] | 0.02 | 27 | 0.24 | 68.5 |
rs1799793 | |||||||
Dominant model | 5 | 256/1687 | 1.15 [0.86, 1.53] | 0.34 | 0 | 0.41 | 16.9 |
 Early adverse effect | 4 | 130/1287 | 1.36 [0.96, 1.92] | 0.09 | 0 | 0.75 | 35.2 |
 Acute skin toxicity | 2 | 84/529 | 1.48 [0.97, 2.26] | 0.07 | 0 | 0.42 | 31.9 |
Recessive model | 3 | 236/1540 | 0.67 [0.41, 1.08] | 0.10 | 0 | 0.49 | 38.9 |
Allelic model | 3 | 236/1540 | 0.99 [0.80, 1.23] | 0.95 | 44 | 0.17 | 5.1 |
rs1052555 | |||||||
Dominant model | 2 | 46/758 | 0.98 [0.53, 1.80] | 0.95 | 0 | 0.74 | 5.1 |