Table 1 Characteristics of the 90 BM patients analyzed
From: Prognostic indices in stereotactic radiotherapy of brain metastases of non-small cell lung cancer
Characteristics | No./median (range) | % |
|---|---|---|
Sex (m/f) | 57/33 | 63.3 %/36.7 % |
Age (y) | 63.3 (38.9–83) | |
KPS | ||
100 | 6 | 6.7 % |
90 | 12 | 13.3 % |
80 | 25 | 27.8 % |
70 | 21 | 23.3 % |
60 | 6 | 6.7 % |
50 | 7 | 7.8 % |
n/a | 13 | 14.4 % |
Histology | ||
Adenocarcinoma | 55 | 61.1 % |
Squamous cell carcinoma | 19 | 21.1 % |
Large cell carcinoma | 6 | 6.7 % |
Other | 8 | 8.9 % |
n/a | 2 | 2.2 % |
UICC stage at time of first diagnosis | ||
I | 5 | 5.6 % |
II | 7 | 7.8 % |
III | 7 | 7.8 % |
IV | 67 | 74.4 % |
n/a | 4 | 4.4 % |
Synchronous BM | 42 | 46.7 % |
ECM | 51 | 56.7 % |
Number of treated lesions | ||
1 | 55 | 61.1 % |
2 | 24 | 26.7 % |
≥ 3 | 11 | 12.2 % |
Total BM volume (PTV) per patient (ccm) | 2.32 (0.2–45.2) | |
Highest BED10 per patient | 91.14 (20.98–97.36) | |
Fractionation | ||
SRS | 108 | 78.8 % |
FSRT | 28 | 20.4 % |
n/a | 1 | 0.7 % |
Localization | ||
Temporal lobe | 15 | 10.8 % |
Occipital lobe | 29 | 20.9 % |
Parietal lobe | 34 | 24.5 % |
Frontal lobe | 28 | 20.1 % |
Cerebellum | 21 | 15.1 % |
Brainstem | 5 | 3.6 % |
Basal ganglia | 4 | 2.9 % |
n/a | 3 | 2.2 % |
Salvage WBRT | 13 | 14.4 % |
Salvage SRS or FSRT | 10 | 11.1 % |
Salvage resection | 5 | 5.6 % |