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Table 1 D 10 values and sensitization ratios for B02, NU7026, and combination of both in H1299 cells

From: Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells

 

D 10

Sensitization ratio

C ions

X-rays

C ions

X-rays

Irradiation alone

5.47 ± 0.35

8.83 ± 0.76

1.00

1.00

B02 (10 μM)

4.07 ± 0.23

7.28 ± 0.48

1.34

1.21

NU7026 (10 μM)

2.63 ± 0.31

3.77 ± 0.32

2.08

2.34

B02 + NU7026

2.47 ± 0.32

3.80 ± 0.26

2.21

2.32

  1. D 10 dose giving a survival of 10 %; C ions carbon ions
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Radiation Oncology

ISSN: 1748-717X

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