Table 3 Characteristics of the 2 patients with isolated nodal recurrence related to elective nodal irradiation
From: Efficacy of elective nodal irradiation in skin squamous cell carcinoma of the face, ears, and scalp
Characteristics | Patient 1 | Patient 2 |
|---|---|---|
Age (years) | 64 | 75 |
Subsite | Pinna | Temple |
First echelon treated | Parotid | Parotid |
Extended elective nodal irradiation | Facial; cervical 1b and 2 | Cervical 2 |
Sex | Male | Male |
Race | White | White |
American Joint Committee on Cancer, 7th ed., stage | T4 | T1 |
Proposed 2013 Journal of American Medical Association stage7 | T2A | T2A |
Axial imaging performed | Yes | Yes |
Immunosuppressed | Yes | No |
Cancer touches midline | No | No |
Clinical perineural invasion | No | No |
Pathological perineural invasion | Yes | No |
>2 cm primary | No | No |
>5 mm thickness | No | No |
>2 mm invasion | No | No |
Invaded subcutaneous fat | No | No |
Lymphovascular space invasion | Yes | No |
Bone invasion on pathology or imaging | No | No |
Cartilage invasion on pathology or imaging | No | No |
Recurrent after curative-intent surgery | Yes | Yes |
Days from first surgery to radiotherapy start | 244 | 323 |
Positive or close margin | Yes | No |
Histology | Moderate | Poor |
Adjuvant (postoperative) without visible tumor | Yes | Yes |
Primary (Gy) | 60 (once daily) | 74 (twice daily) |
1st Echelon (Gy) | 46 (once daily) | 74 (twice daily) |
Rest (Gy) | 50 (once daily) | 46 (once daily) |