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Table 3 Real-time RT-PCR results in groups with/without preoperative RT and with/without postoperative cervical WHDs

From: An expression analysis of markers of radiation-induced skin fibrosis and angiogenesis in wound healing disorders of the head and neck

Gen

Median expression per GAPDH

Median expression per GAPDH

 

RT

No RT

 

WHD

No WHD

 
 

N (%)

N (%)

p Value

N (%)

N (%)

p Value

α-Procollagen

9.1 E-01

2.1 E-01

0.002*

7.4 E-01

2.5 E-01

0.067

 

18 (36.7)

31 (63.3)

 

15 (40.5)

22 (59.5)

 

TGF-β1

2.3 E-03

1.1 E-03

0.012*

1.2 E-03

2.1 E-03

0.245

 

18 (38.3)

29 (61.7)

 

15 (40.5)

22 (59.5)

 

vWF

4.3 E-02

1.5 E-01

0.005*

7.8 E-02

1.6 E-01

0.080

 

9 (20.5)

35 (79.5)

 

10 (35.7)

18 (64.3)

 
  1. Abbreviations: WHD wound healing disorder, RT radiation therapy, RT-PCR reverse-transcription polymerase chain reaction
  2. Data in parentheses are percentages, unless noted otherwise; *statistically significant difference at α=0.0
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Radiation Oncology

ISSN: 1748-717X

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