Table 2 Results between ENI and IFRT
| Â | ENI | IFRT | p value | ||
|---|---|---|---|---|---|
N | % | N | % | ||
State at analysis | |||||
 Alive | 20 | 17 % | 71 | 60 % | <0.0001 |
 Dead | 100 | 84 % | 48 | 40 % |  |
Follow-up time of all cases | |||||
 Median | 18 mo |  | |||
 Range | 1–169 mo |  | |||
Follow-up time of alive cases | |||||
 Median | 34 mo |  | |||
 Range | 2–154 mo |  | |||
Residual (= non-CR) | 20 | 17 % | 6 | 5 % | 0.0039 |
First locoregional REC | 41 | 34 % | 30 | 25 % | 0.13 |
 Primary | 30 |  | 23 |  |  |
 Lymph node | 20 |  | 9 |  |  |
 (Elective nodal region) | (4) |  | (2) |  |  |
 Both | 9 |  | 2 |  |  |
First distant REC | 48 | 40 % | 25 | 21 % | 0.0014 |
 Lymph node | 13 |  | 7 |  |  |
 Lung | 20 |  | 8 |  |  |
 Bone | 6 |  | 3 |  |  |
 Liver | 6 |  | 5 |  |  |
Salvage surgery after REC | 11 | 9 % | 3 | 3 % | 0.029 |
Grade 3–5 non-hematological toxicities by RTOG | 19 | 16 % | 9 | 8 % | 0.047 |
 Lung | 7 |  | 3 |  |  |
 Heart | 5 |  | 0 |  |  |
 Esophagus | 2 |  | 2 |  |  |