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Table 6 EORTC QLQ-CR38 scores with respect to tumor location, gender and symptoms of urgency and fecal soiling

From: Long-term effects of neoadjuvant chemoradiotherapy followed by sphincter-preserving resection on anal sphincter function in relation to quality of life among locally advanced rectal cancer patients: a cross-sectional analysis

EORTC QLQ-CR38 components

Total

Tumor location in rectum

Gender

Urgency

Fecal soiling

Prox.

Mid.

Distal

 

F

M

 

(+)

(−)

 

(+)

(−)

 

Functional scales

Median (min-max)

Median (min-max)

Pa

Median (min-max)

Pa

Median (min-max)

Pa

Median (min-max)

P a

 Body image (n = 26)

77.8 (33.3–100)

88.9 (55.6–100)

66.7 (33.3–100)

94.4 (33.3–100)

NA

88.9 (33.3–100)

61.1 (33.3–100)

0.274

66.7 (33.3–100)

100 (33.3–100)

0.151

66.7 (33.3–100)

77.8 (33.3–100)

0.469

 Future perspective (n = 25)

66.7 (0–100)

83.3 (66.7–100)

66.7 (0–100)

66.7 (0–100)

NA

66.7 (0–100)

66.7 (0–100)

0.727

66.7 (0–100)

100 (66.7–100)

0.010

66.7 (33.3–100)

66.7 (0–100)

0.855

 Sexual functioning (n = 29)

33.3 (0–66.7)

8.3 (0–33.3)

33.3 (0–66.7)

33.3 (0–66.7)

NA

0 (0–66.7)

33.3 (0–66.7)

0.172

0 (0–66.7)

33.3 (16.7–66.7)

0.016

16.7 (0–50)

33.3 (0–66.7)

0.521

 Sexual enjoyment (n = 24)

0 (0–66.7)

0 (0–33.3)

0 (0–33.3)

0 (0–66.7)

NA

0 (0–33.3)

0 (0–66.7)

0.977

0 (0–33.3)

0 (0–66.7)

0.634

0 (0–0)

0 (0–66.7)

0.273

Symptom scales

 Rad-induced micturition (n = 29)

22.2 (0–77.8)

16.7 (0–44.4)

22.2 (0–55.6)

27.8 (0–77.8)

NA

11.1 (0–77.8)

33.3 (0–66.7)

0.112

22.2 (0.7–7.8)

5.6 (0–66.7)

0.206

22.2 (11.1–66.7)

11.1 (0–77.8)

0.250

 Chemotherapy side effects (n = 29)

11.1 (0–100)

27.8 (0–100)

11.1 (0–33.3)

11.1 (0–33.3)

NA

11.1 (0–100)

11.1 (0–33.3)

0.477

11.1 (0–100)

0 (0–22.2)

0.023

11.1 (0–22.2)

11.1 (0–100)

0.304

 Gastrointesti-nal symptoms (n = 29)

20 (0–60)

30 (0–60)

6.7 (0–53.3)

20 (0–53.3)

NA

20 (0–60)

13.3 (0–53.3)

0.425

20 (0–60)

6.7 (0–26.7)

0.114

20 (0–53.3)

16.7 (0–60)

0.685

 Sexual dysfunction of men (n = 11)

50 (0–100)

0 (0–0)

100 (33.3–100)

41.7 (16.7–100)

NA

–

50 (0–100)

NA

58.3 (16.7–100)

16.7 (0–100)

0.294

33.3 (0–100)

75 (16.7–100)

0.496

 Sexual dysfunction of women (n = 4)

0 (0–50)

50 (50–50)

–

0 (0–0)

NA

50 (0–100)

–

NA

0 (0–0)

0 (0–50)

NA

–

0 (0–50)

0.113

 Defecation problems (n = 29)

33.3 (0–85.7)

23.8 (4.8–42.9)

33.3 (0–81)

33.3 (4.8–85.7)

NA

30.9 (0–57.1)

33.3 (0–85.7)

0.425

38.1 (4.8–85.7)

7.1 (0–33.3)

0.001

38.1 (4.8–85.7)

30.9 (0–81)

0.502

 Weight loss (n = 29)

0 (0–100)

0 (0–100)

0 (0–66.7)

0 (0–33.3)

N/A

0 (0–100)

0 (0–66.7)

0.621

0 (0–100)

0 (0–0)

0.097

0 (0–33.3)

0 (0–100)

1.00

  1. aMann-Whitney U test
  2. F Female, M Male, NA Not applicable (n < 30), Rad Radiation. Bold values indicate statistical significance at α=0.05 level