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Table 4 Univariant and multivariant analysis of potential factors associated with postoperative complications

From: Clinical features, outcome and risk factors in cervical cancer patients after surgery for chronic radiation enteropathy

 

Overall morbidity

Major morbidity

(grade I–V)

(grade III–V)

 

Univariant

Multivariant

 

Univariant

Multivariant

 

Variables

P value

P value

OR(95 % CI)

P value

P value

OR(95 % CI)

Anemia (Y/N)

0.023

0.015

2.626(1.204–5.728)

0.473

-

-

Time interval from disease onset to surgery (<6 m/>6 m)

0.000

0.062

0.527(0.269–1.364)

0.181

-

-

Chemotherapy (Y/N)

0.023

0.307

0.7(0.353–1.388)

1.000

-

-

Operation time

0.092

0.210

1.588(0.770–3.277)

0.816

-

-

(<150/>150) min

      

Adhesion states in surgical site (IV-V/I-III)

0.046

0.089

2.180(0.887–5.360)

0.066

0.017

3.535(1.250–10.001)

ASA grade (III–V/I-II)

1.000

-

-

0.014

0.022

3.400(1.197–9.653)

RTOG/ETORC Grade IV late morbidity (Y/N)

0.129

-

-

0.001

0.018

0.171(0.040–0.735)

Stomy surgery (Y/N)

0.617

-

-

0.039

0.575

1.723(0.257–11.546)

Staged surgery (I/II)

0.492

-

-

0.099

0.735

0.731(0.120–4.474)

Age (<50/>50) y

0.624

-

-

1.000

-

-

Tumor stage (I-IIa/IIb-V)

0.496

-

-

0.702

-

-

Pathological type (squamous carcinoma/adenocarcinoma)

0.710

-

-

1.000

-

--

Radiation dosage (Gy)

0.373

-

-

0.379

-

-

Acute radiation enteritis (Y/N)

0.475

-

-

0.807

-

-

Previous abdominal surgery (Y/N)

0.345

-

-

0.789

-

-

Latency period (m)

0.194

-

-

0.369

-

-

Hypertention (Y/N)

0.569

-

-

0.108

-

-

Diabetes mellitus (Y/N)

0.616

-

-

0.453

-

-

BMI < 18.5 and weight loss >10 %

0.217

-

-

1.000

-

-

Preoperative TPN (Y/N)

0.407

-

-

0.493

-

-

Short bowel syndrome (Y/N)

0.330

-

-

1.000

-

-

  1. RTOG/ETORC the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC), ASA American Society of Anesthesiologists, BMI Body mass Index