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Table 4 Effects of variables on OS and DSS

From: Textural features in pre-treatment [F18]-FDG-PET/CT are correlated with risk of local recurrence and disease-specific survival in early stage NSCLC patients receiving primary stereotactic radiation therapy

Parameter

Overall survival

Disease-specific survival

Univariate

Multivariate

Univariate

Multivariate

HR

p

HR

p

HR

P

HR

P

Age

1.07 (0.70–1.65)

.746

  

0.78 (0.42–1.44)

.424

  

SUVmax

0.97 (0.72–1.29)

.819

  

1.06 (0.74–1.51)

.761

  

SUVmean

1.00 (0.31–3.25)

.994

  

1.71 (0.37–7.59)

.480

  

High entropy

1.85 (0.85–4.00)

.120

1.79 (0.70–4.59)‡

.225

5.92 (1.2827.4)

.023

9.52 (1.3965.1)

.022

High correlation

1.58 (0.72–3.47)

.250

  

2.35 (0.74–7.44)

.146

1.61 (0.44–5.90)‡

.474

High contrast

0.90 (0.43–1.92)

.793

  

1.56 (0.46–5.30)

.476

  

High busyness

1.55 (0.62–3.84)

.347

  

2.70 (0.65–8.56)

.093

1.29 (0.14–12.2)‡

.822

High coarseness

0.68 (0.30–1.52)

.346

  

0.37 ( 0.12–1.18)

.093

0.77 (0.08–7.28)‡

.822

High COV

1.52 (0.71–3.25)

.278

  

2.65 (0.79–8.91)

.114

1.98 (0.52–7.53)‡

.401

MTV*

1.02 (0.99–1.06)

.223

1.55 (0.27–8.95)†

.623

1.06 (1.011.12)

.031

2.11 (0.12–38.1)†

.613

CT diameter

1.01 (0.98–1.04)

.555

  

1.03 (0.98–1.07)

.245

  
  1. †tested against entropy, cumulative dose and CT diameter ‡tested against MTV, cumulative dose and CT diameter.
  2. *analyzed on log scale.
  3. Significant values are printed in bold.