Table 2 Characteristics of patients with or without anastomotic stenosis, treated with neo-adjuvant chemoradiation followed by transhiatal esophagectomy

Mean age

61.3 [41–78]

65.4 [48–82]

0.30

Gender:

 Male (n = 49)

21 (43%)

28 (57%)

 Female (n = 4)

3 (75%)

1 (25%)

0.32

BMI

26.6 [19–41]

26.7 [21–35]

0.68

Co-morbidity:

 0 (n = 13)

9 (69%)

4 (31%)

 1 (n = 18)

8 (44%)

10 (56%)

 2 or more (n = 22)

7 (32%)

15 (68%)

0.10

ASA classification:

 I (n = 8)

4 (50%)

4 (50%)

 II (n = 41)

19 (46%)

22 (54%)

 III (n = 4)

1 (25%)

3 (75%)

0.69

Histologic type:

 Adenocarcinoma (n = 49)

22 (45%)

27 (55%)

 Squamous cell carcinoma (n = 4)

2 (50%)

2 (50%)

0.84

Volume (cm³)

48.3 [29–81]

48.1 [21–92]

0.92

Mean dose (Gy)

31.2 [6–42]

29.6 [8–42]

0.38

V20

84.9%

83.4%

0.27

V25

68.8%

58.5%

0.24

V30

59.5%

50.1%

0.30

V35

52.9%

43.1%

0.28

V40

40.1%

28.8%

0.14

OR time (min)

184 [118–329]

182 [138–292]

0.75

Resection type:

 Open (n = 21)

11 (52%)

10 (48%)

 Laparoscopic (n = 32)

13 (41%)

19 (59%)

0.40

Method of anastomosis:

 End-to-end continuous (n = 33)

15 (45%)

18 (55%)

 End-to-end interrupted (n = 11)

7 (64%)

4 (36%)

 Side-to -side stapler (n = 9)

2 (22%)

7 (78%)

0.18

Interval last RT– surgery (days)

65 [37–118]

73 [31–127]

0.31

Hospital stay (days)

14 [6–35]

16 [6–71]

0.63

Anastomotic leakage (n = 13)

7 (54%)

6 (46%)

0.48