|
Genes
|
D’
|
r
2
|
Hap
|
Freq
|
P
cor
|
1-β
|
SS
0.8
|
|---|
|
PON1
| | | | | | | |
|
rs662-rs705379
|
0.871
|
0.294
|
TC
|
0.290
|
0.0158
|
0.849
|
117
|
|
CT
|
0.446
|
0.1881
|
|
TT
|
0.019
|
0.6840
|
|
CC
|
0.245
|
0.9740
|
|
ADIPOQ
| | | | | | | |
|
rs1501299- rs2241766
|
1
|
0.168
|
GG
|
0.301
|
0.9740
|
0.047
|
1047
|
|
TG
|
0.418
|
0.9740
|
|
TT
|
0.281
|
0.9740
|
|
TGFB1
| | | | | | | |
|
rs4803455- rs1800470
|
0.88
|
0.628
|
CG
|
0.573
|
0.8766
|
0.033
|
1363
|
|
AA
|
0.326
|
0.8766
|
|
AG
|
0.025
|
0.8766
|
|
CA
|
0.076
|
0.9740
|
|
rs1800470-rs1800469
|
1
|
0.936
|
AG
|
0.391
|
0.8766
|
0.061
|
875
|
|
GA
|
0.594
|
0.8766
|
|
AA
|
0.012
|
0.9740
|
|
rs4803455-rs1800470-rs1800469
|
0.883
|
0.648
|
AAG
|
0.322
|
0.8766
|
0.097
|
638
|
|
CGA
|
0.573
|
0.8766
|
|
CAG
|
0.069
|
0.9740
|
|
AGA
|
0.021
|
0.9740
|
- Five haplotype windows (HWs) include rs662-rs705379, rs1501299-rs2241766, rs4803455-rs1800470, rs1800470-rs1800469, and rs4803455-rs1800470-rs1800469. Post-RT duration and number of cardiovascular risk factors were adjusted using linear regression in all analyses. Multiple testing was corrected by false discovery rate. Statistical power (1-β) was calculated using the model with smallest observed P value. SS0.8 was the sample size to achieve a statistical power of 0.8 in the corresponding analysis. Hap, haplotype; Freq, frequency; P
cor
, Corrected P value.
