Impact of head and neck cancer adaptive radiotherapy to spare the parotid glands and decrease the risk of xerostomia

Table 1 Patient, tumor, and treatment characteristics at the initial planning (CT0)

ID	Gender	Age	Tumor localization	TNM	Volume (cc)			D _mean (Gy)		Xerostomia NTCP (%) [ 21 ]
					CTV70	HLP	CLP	HLP	CLP	Xerostomia NTCP (%) [ 21 ]
					CTV70	HLP	CLP	HLP	CLP	HLP	CLP
1	M	86	Tonsil	T3N1	45.2	52.1	48.6	30.2	31.1	26.5	28.3
2	F	63	Tonsil	T2Nx	26.3	31.1	27.5	31.4	26	29.0	18.7
3	M	74	Oropharynx	T3N2c	181.5	24.9	20.7	37.9	31.1	44.3	28.4
4	F	66	Oropharynx	T2N2c	107.2	27.8	23.4	32.9	27.9	32.3	22.0
5	M	57	Velum	T3N0	62.4	20.7	18.0	28.1	27.8	22.4	21.7
6	M	67	Oropharynx	T3N2c	156.2	24.5	22.7	30.8	29.4	24.7	21.4
7	M	52	Oropharynx	T4N2	165.1	N/A	21.6	N/A	28.7	N/A	23.4
8	M	67	Trigone	T4N1	139.3	22.0	19.3	30.7	29.2	27.4	24.4
9	F	65	Oropharynx	T3N3	237.5	23.9	20.2	42.4	31.1	55.2	28.2
10	F	65	Oropharynx	T4N3	257.9	N/A	24.5	N/A	35.2	N/A	37.7
11	M	50	Oropharynx	T4N2c	434.5	N/A	17.7	N/A	36.3	N/A	40.3
12	M	53	Oropharynx	T3N0	14.4	16.6	23.3	41.3	24.2	52.9	15.9
13	M	73	Oropharynx	T3N2c	147.0	29.4	29.2	54.6	32.2	81.7	30.7
14	M	56	Larynx	T3N0	14.0	22.8	29.2	19.7	9.2	10.1	2.7
15	M	75	Hypopharynx	T2N2	76.3	20.3	22.4	29.4	29.1	25.0	24.4

M: male; F: female; CT0: initial planning; CTV70: clinical target volume receiving 70 Gy; PGs: parotid glands; HLP: homolateral PGs; CLP: contralateral PGs; Dmean: mean dose at initial planning; N/A: not applicable (PGs included in the CTV), NTCP: normal tissue complication risk of xerostomia defined as a salivary flow ratio <25% of the pretreatment one [21].

ISSN: 1748-717X