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Table 5 Multivariate analysis for overall survival, disease free survival, and distant metastases

From: Pre-radiotherapy feeding tube identifies a poor prognostic subset of postoperative p16 positive oropharyngeal carcinoma patients

Overall survival

HR (95% CI)

p-value

FT Group

Ā Ā 

ā€ƒB-FT vs. NO-FT

6.0 (2.0 ā€“ 18.6)

0.0013

ā€ƒDA-FT vs. NO-FT

1.5 (0.4 ā€“ 5.4)

Age (years)

Ā Ā 

ā€ƒā‰„50 vs. < 50

2.1 (0.8 ā€“ 5.3)

0.1165

Smoking

Ā Ā 

ā€ƒ<20 pack-years vs. never smoker

3.6 (0.8 ā€“ 16.9)

0.0182

ā€ƒā‰„20 pack-years vs. never smoker

5.0 (1.6 ā€“ 15.3)

Disease Free Survival

Ā Ā 

FT Group

Ā Ā 

ā€ƒB-FT vs. NO-FT

4.7 (1.7 ā€“ 13.1)

0.0017

ā€ƒDA-FT vs. NO-FT

1.3 (0.4 ā€“ 4.0)

Age (years)

Ā Ā 

ā€ƒā‰„50 vs. < 50

2.3 (1.0 ā€“ 5.4)

0.0619

Smoking

Ā Ā 

ā€ƒ<20 pack-years vs. never smoker

2.2 (0.5 ā€“ 9.5)

0.0316

ā€ƒā‰„20 pack-years vs. never smoker

3.8 (1.4 ā€“ 10.6)

Distant Metastases Free Survival

Ā Ā 

Group

Ā Ā 

ā€ƒB-FT vs. NO-FT

0.91 (0.17 ā€“ 5.02)

0.9942

ā€ƒDA-FT vs. NO-FT

0.95 (0.21 ā€“ 4.27)

Age (years)

Ā Ā 

ā€ƒā‰„50 vs. < 50

3.7 (0.8 ā€“ 17.8)

0.1053

  1. Abbreviations: B-FT Feeding tube placement before IMRT, DA-FT Feeding tube placement during or after IMRT, NO-FT No feeding tube, TLM Transoral laser microsurgery, CI Confidence interval.