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Table 1 Selected median (range) dosimetric indices of the optimized plans

From: Dosimetric robustness against setup errors in charged particle radiotherapy of skull base tumors

Planning approach

Dosimetric index

 

Carbon ion plans

 

Proton plans

  

ucLR

scLR

mcLR

mcROB

 

ucLR

mcLR

mcROB

PTV V95%

 

99.2

97.9

98.3

98.3

 

97.2

95.2

95.8

[%]

 

(98.3-99.7)

(93.1-99.1)

(95.0-99.3)

(95.2-98.7)

 

(96.0-99.3)

(90.4-97.7)

(93.1-97.3)

CTV V95%

 

100.0

99.7

99.8

99.7

 

99.5

98.8

99.2

[%]

 

(99.9-100.0)

(97.3-100.0)

(98.5-100.0)

(98.8-100.0)

 

(99.2-99.8)

(95.5-99.6)

(97.8-100.0)

PTV HI

 

5.9

7.8

7.7

7.8

 

11.2

13.9

12.5

[p p]

 

(4.5-8.1)

(6.0-11.1)

(5.5-10.3)

(6.6-10.8)

 

(6.3-12.9)

(9.9-14.9)

(9.5-13.8)

CTV HI

 

4.0

4.8

4.6

5.0

 

7.9

9.4

8.7

[p p]

 

(3.4-5.0)

(3.6-8.2)

(3.7-7.7)

(4.5-7.3)

 

(5.1-9.3)

(7.0-12.5)

(6.3-9.9)

PTV CI

 

0.85

0.87

0.87

0.86

 

0.78

0.79

0.78

[−]

 

(0.81-0.91)

(0.80-0.91)

(0.82-0.91)

(0.82-0.89)

 

(0.70-0.88)

(0.71-0.87)

(0.71-0.84)

Dnear-max brainstem

 

n/a

53.9

52.9

52.2

 

n/a

61.0

60.2

[Gy(RBE) ]

  

(38.8-55.0)

(35.6-54.2)

(36.9-54.3)

  

(45.5-63.1)

(46.3-62.6)

Dmax chiasm

 

n/a

54.0

53.9

53.8

 

n/a

58.1

59.9

[Gy(RBE) ]

  

(0.0-54.2)

(0.0-54.1)

(52.6-54.1)

  

(0.0-60.1)

(59.0-60.2)

Dmax ips. optic nerve

 

n/a

54.0

53.8

53.8

 

n/a

59.7

60.1

[Gy(RBE) ]

  

(0.0-54.2)

(0.0-54.2)

(40.6-54.1)

  

(0.0-60.3)

(50.9-60.4)

Dmax con. optic nerve

 

n/a

42.9

43.3

39.2

 

n/a

51.2

42.5

[Gy(RBE) ]

  

(0.0-54.2)

(0.0-54.2)

(0.0-53.9)

  

(0.0-60.5)

(0.0-59.8)

  1. Abbreviations: CTV clinical target volume, PTV planning target volume, ips ipsilateral, con contralateral, LR lateral-opposed beam setup, ROB robust beam setup, uc unconstrained mode, sc single-field modulation, mc multiple-field modulation, pp percentage point, n/a not applicable.